nepetin/edema

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Heme oxygenase 1-mediated novel anti-inflammatory activities of Salvia plebeia and its active components.

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BACKGROUND Salvia plebeia R. Br. (SP) has been widely used as a traditional folk medicine for the treatment of infectious diseases and pain. An anti-inflammatory potential of SP has remains largely unknown. OBJECTIVE We tried to elucidate the principle mechanism and the active ingredients underlying

Anti-inflammatory activity of flavonoids from Eupatorium arnottianum.

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Three anti-inflammatory compounds: nepetin, jaceosidin and hispidulin have been isolated and identified from Eupatorium arnottianum Griseb. dichloromethane extract. Nepetin reduced the TPA mouse ear edema by 46.9% and jaceosidin by 23.2% (1mg/ear). Both compounds inhibited the NF kappaB induction by

Anti-phospholipase A2 and anti-inflammatory activity of Santolina chamaecyparissus.

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The activity of the Santolina chamaecyparissus methanol extract was tested against the phospholipase A2 (PLA2)-induced mouse paw edema and in vitro inhibition of PLA2 activity. After fractionation, only the dichloromethane extract was active against the PLA2 in vitro test. In addition, it reduced

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