notoginsenoside/obesity

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Development and validation of an UFLC-MS/MS assay for the absolute quantitation of nine notoginsenosides in rat plasma: Application to the pharmacokinetic study of Panax Notoginseng Extract.

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Notoginsenosides, the main active gradients of Chinese traditional medicine Panax notoginseng, possesses a variety of biological activities including antioxidant property, anti-hyperglycemic, anti-obese, etc. However, pharmacokinetic evaluation for notoginsenosides is still a formidable task due to

[Major hypoglycemic ingredients of Panax notoginseng saponins for treating diabetes].

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OBJECTIVE To explore the mechanism of Panax notoginseng saponins (PNS) on diabetes treatment and mass loss in KK-Ay mice with genetic type 2 diabetes mellitus (DM), and to identify the main hypoglycemic ingredients. METHODS C57 and KK-Ay DM mice were divided into eight groups each comprising six

Anti-diabetic effects of Panax notoginseng saponins and its major anti-hyperglycemic components.

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BACKGROUND Panax notoginseng (Burk) F.H. Chen (Araliaceae) is a well-known and commonly used traditional Chinese herb for treatment of various diseases, such as hemostasis, edema and odynolysis. OBJECTIVE Our aim was to investigate the mechanisms of anti-hyperglycemic and anti-obese effects of Panax

Ginsenoside Rb1 as an Anti-Diabetic Agent and Its Underlying Mechanism Analysis.

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Panax ginseng and Panax notoginseng, two well-known medical plants with economic value, have a long history of use for managing various diseases in Asian countries. Accumulating clinical and experimental evidence suggests that notoginsenosides and ginsenosides, which are the major

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