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The cytosolic phospholipase A2α(cPLA2α) is one of the potential targets for anti-inflammatory drugs, since this enzyme plays a key role in the inflammation processes seen in health disorders, like asthma, allergic reactions, arthritis and neuronal diseases. In this study, cPLA2α inhibition by 43
Ononis species are used for their laxative, diuretic, analgesic, anti-inflammatory, antiviral, cytotoxic and antifungal effects as well as against skin diseases for wound healing activity. In the light of this information n-hexane, ethylacetate and methanol extracts prepared from Ononis spinosa L.
BACKGROUND
Dried roots of Ononis spinosa L. are traditionally used for their diuretic, anti-inflammatory and wound healing effects.
OBJECTIVE
Isolation of the bioactive compounds of Ononis spinosa L. subsp. leiosperma (Boiss.) Sirj.
METHODS
Ethyl acetate extract prepared from the roots of Ononis