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Paj 1 soti nan 22 rezilta yo
Oripavine - a new opium alkaloid.
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Oripavine was isolated from the dried capsules of a variety of PAPAVER SOMNIFERUM cultivated on Tasmania.
Transformation of thebaine to oripavine, codeine, and morphine by rat liver, kidney, and brain microsomes.
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Thebaine, an intermediate of morphine biosynthesis in the poppy plant, Papaver somniferum, was transformed to oripavine, codeine, and morphine by rat liver, kidney, and brain microsomes in the presence of an NADPH-generating system. The formation of morphine, codeine, and oripavine was identified by
Biosynthesis of opium alkaloids. Substrate specificity and aberrant biosynthesis: attempted detection of oripavine in Papaver somniferum.
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Microbe associated molecular patterns from rhizosphere bacteria trigger germination and Papaver somniferum metabolism under greenhouse conditions.
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Ten PGPR from different backgrounds were assayed on Papaver somniferum var. Madrigal to evaluate their potential as biotic elicitors to increase alkaloid content under the rationale that some microbe associated molecular patterns (MAMPs) are able to trigger plant metabolism. First, the 10 strains
Rapid determination of Papaver somniferum alkaloids in process streams using monolithic column high-performance liquid chromatography with chemiluminescence detection.
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We have combined high-performance liquid chromatography (HPLC) separations using a monolithic column with acidic potassium permanganate and tris(2,2'-bipyridyl)ruthenium(II) chemiluminescence detection in a rapid and highly sensitive method to monitor the process of extracting opiate alkaloids from
Development and validation of a reversed-phase HPLC method for determination of alkaloids from Papaver somniferum L. (Papaveraceae).
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An HPLC method for the separation of six target alkaloids from Papaver somniferum L. (morphine, codeine, oripavine, thebaine, papaverine, and noscapine) was developed, optimized, and validated. The chromatographic behavior of these alkaloids was investigated using a reversed-phase chromatography at
Salutaridine N-Oxide from the Capsules of Papaver bracteatum.
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A novel compound, salutaridine N-oxide ( 1) has been isolated from PAPAVER BRACTEATUM Lindl (Papaveraceae) in which the major alkaloids were salutaridine and thebaine. Semisynthetic 1 was prepared for structure confirmation. Other components of the alkaloidal fraction were isothebaine, oripavine,
Rapid semi-quantitative spot test for determination of thebaine and differentiation of Papaver bracteatum from P. orientale and P. pseudo-orientale.
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The alkaloids, orientalidine, oripavine, thebaine, narceine, narceine, codeine, papaverine, isothebaine, alpenigenine and morphine react with a solution of sulfuric acid containing molybdate to give specific colors. Using the acid solution permitted the differentiation of Papaver bracteatum latex
Biosynthesis of unnatural papaverine derivatives in Papaver somniferum.
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The unnatural thebaine analog, oripavine 3-ethyl ether, was efficiently metabolized to morphine 3-ethyl ether and morphine in the opium poppy. An attempt to detect oripavine hy an isotope dilution experiment based on its presumed biosynthesis from reticuline was unsuccessful.
Crystal structure of thebaine 6-O-demethylase from the morphine biosynthesis pathway.
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Thebaine 6-O-demethylase (T6ODM) from Papaver somniferum (opium poppy), which belongs to the non-heme 2-oxoglutarate/Fe(II)-dependent dioxygenases (ODD) family, is a key enzyme in the morphine biosynthesis pathway. Initially, T6ODM was characterized as an enzyme catalyzing O-demethylation of
Alkaloids from Papaver cylindricum.
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The major alkaloids obtained from Papaver cylindricum Cullen were oripavine, narcotine, thebaine and rhoeadine. Floripavidine, papaverine, salutaridine, armepavine, N-methylasimilobine, scoulerine and cheilanthifoline were obtained as minor alkaloids. There have been no previous reports of alkaloids
Alkaloids of Papaver orientale and papaver pseudo-orientale.
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Dry latex of Paaver orientale was shown to contain 20% oripavine and 9% thebaine. Dry latex of Papaver pseudo-orientale contained two major alkaloids, isothebaine (11.7%) and orientalidine (0.5%), and the minor alkaloids bracteolin, salutaridine, Or1, Or2, PO-4, alborine (PO-5), and a novel alkaloid
Analysis of fluid extracts obtained from Papaver rhoeas petals contaminated with Papaver bracteatum petals.
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In this paper, we report a case of misidentification of medicinal plants involving dried petals of Papaver rhoeas (red poppy) contaminated with Papaver bracteatum (scarlet poppy) petals. Preliminary TLC analysis indicated the presence of thebaine either in the fluid extracts or in the petals. It was
[Quality and quantity of morphinan alkaloids detectable in interspecific hybrids of the genus papaver*].
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Viable hybrids were artificially produced between PAPAVER BRACTEATUM rich in thebaine on the one side and PAPAVER SOMNIFERUM, PAPAVER ORIENTALE and PAPAVER PSEUDO-ORIENTALE on the other side. Each of them is characterized by morphological and some physiological features as well as by its chromosome
Update of the Scientific Opinion on opium alkaloids in poppy seeds
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Poppy seeds are obtained from the opium poppy (Papaver somniferum L.). They are used as food and to produce edible oil. The opium poppy plant contains narcotic alkaloids such as morphine and codeine. Poppy seeds do not contain the opium alkaloids, but can become contaminated with alkaloids as
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