phytohemagglutinin/sambucus

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Effects of metabolic inhibitors and lectins on the menadione-dependent generation of H2O2 by rat thymocytes.

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The capacity of oxidative metabolism and its regulation is an important factor in disease control. Using scopoletin as a fluorescent substrate of peroxidase the extent of menadione-dependent production of H2O2 by rat thymocytes was determined. The reaction was inhibited by 2,4-dinitrophenol,

[Changes of alkaline phosphatase sugar chains in hepatocellular carcinoma tissue].

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OBJECTIVE To investigate the changes of sugar chain structures of alkaline phosphatase (ALP) in hepatoma tissue and its relation to the invasiveness of hepatocellular carcinoma (HCC). METHODS The binding ratios of ALP from 9 normal liver tissues, 16 hepatoma tissues and 16 noncancerous tissues

Dietary lectins can induce in vitro release of IL-4 and IL-13 from human basophils.

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Dietary lectins, present in beans and other edible plant products, pose a potential threat to consumers due to their capacity to induce histamine release from basophils. In this study, we analyzed the capacity of 16 common, in particular dietary, lectins to induce human basophils to secrete IL-4 and

Aberrant glycosylation of αvβ3 integrin is associated with melanoma progression.

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N-glycosylation of integrins plays an important role in cancer progression. Increased αvβ3 integrin expression during melanoma progression is well-documented but the role of its glycans in tumorigenesis is still poorly understood. In the present study we used the WM793 primary melanoma cell line and

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