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rauwolscine/stroke
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Cardiovascular responses to the stimulation of alpha-1 and alpha-2 adrenoceptors in the conscious dog.
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Hemodynamic responses to the selective stimulation of alpha-1 and alpha-2 adrenoceptors were examined in chronically instrumented, conscious dogs. Norepinephrine (0.02-0.1 micrograms/kg/min), a mixed alpha-1/alpha-2 adrenoceptor agonist, phenylephrine (0.2-1.0 micrograms/kg/min), a selective
Phenylpropanolamine constricts mouse and human blood vessels by preferentially activating alpha2-adrenoceptors.
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Phenylpropanolamine (dl-norephedrine) was one of the most widely used therapeutic agents to act on the sympathetic nervous system. Because of concerns regarding incidents of stroke, its use as a nasal decongestant was discontinued. Although considered an alpha1-adrenergic agonist, the vascular
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