refractive errors/hypoxia

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[Changes in myopic refractive errors after 9 months of extensive wear of hydrogel lenses with high oxygen permeability and compared with those with low permeability].

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BACKGROUND A small but significant increase in myopia after extended wear of low oxygen permeability (Dk) hydrogel lenses has been previously reported; however, the specific impact of hypoxia on refractive status and corneal curvature with extended wear are not well documented. THE PURPOSE of this

Changes in myopic refractive error with nine months' extended wear of hydrogel lenses with high and low oxygen permeability.

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Clinical signs of hypoxia with high-Dk soft lens extended wear: is the cornea convinced?

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OBJECTIVE To assess the effectiveness of high-Dk soft contact lenses with oxygen transmissibility (Dk/L) beyond the critical level required to avoid corneal edema during overnight wear. METHODS The most up-to-date data available on clinical signs of hypoxia with high-Dk contact lenses is

Have silicone hydrogel lenses eliminated hypoxia?

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OBJECTIVE The purpose of this article is to review the literature to date to determine if silicone hydrogel lenses have eliminated corneal hypoxia. METHODS Results from clinical studies, including short-term laboratory studies and retrospective and prospective clinical trials that have assessed the

Acute hypoxia influences collagen and matrix metalloproteinase expression by human keratoconus cells in vitro.

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Keratoconus (KC) is a progressive corneal ectasia linked to thinning of the central cornea. Hard contact lenses, rigid gas permeable lenses, and scleral lenses are the primary treatment modalities for early to mid- stages of KC to correct refractive error and astigmatism that develops as a result of

Retinal Vascular Oxygen Saturation and Its Variation With Refractive Error and Axial Length.

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To evaluate the relationships between refractive error, axial length (AL), and retinal vascular oxygen saturation in an adult population.This was a hospital-based, prospective observational study. The left eyes of phakic adult subjects without media opacity

Corneal oxygen deficiency.

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OBJECTIVE To compare the ocular effects of low Dk hydrogel and high Dk silicone hydrogel contact lenses. METHODS A review of recent literature was conducted to determine the effects of wearing low and high Dk soft lenses on corneal swelling, vascular response, refractive error and the corneal

Central corneal thickness of Iraqi population in relation to age, gender, refractive errors, and corneal curvature: a hospital-based cross-sectional study.

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BACKGROUND Central corneal thickness (CCT) is an important indicator of corneal status. Its measurement provides valid information about corneal physiological condition and possible changes associated with diseases, traumas, and hypoxia. It is an integral part for interpretation of intraocular

The Berkeley Contact Lens Extended Wear Study. Part II : Clinical results.

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OBJECTIVE To describe the principal clinical outcomes associated with 12 months use of rigid gas-permeable (RGP) extended wear contact lenses and address two primary study questions: (1) does extended wear (EW) of high oxygen transmissibility (Dk/t) RGP lenses reduce the incidence of ocular

Objective and subjective responses in patients refitted to daily-wear silicone hydrogel contact lenses.

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OBJECTIVE Silicone hydrogel (SiH) lenses offer many physiological advantages for daily wear (DW) in addition to the continuous-wear modality for which they were originally developed. The purpose of this study was to investigate the clinical performance and physiological responses in a group of

The Berkeley Contact Lens Extended Wear Study. Part I : Study design and conduct.

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OBJECTIVE The primary aim of the Berkeley Contact Lens Extended Wear Study (CLEWS) was to test the hypotheses that extended wear of rigid gas-permeable (RGP) contact lenses with greater oxygen permeability (Dk) reduces the incidence of contact lens-associated keratopathy (CLAK) and increases the

Specular microscopy of hard contact lens wearers.

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Wide-field specular microscopy, slit-lamp examination, and pachometry were performed on 22 successful hard contact lens wearers and 22 controls matched for age, race, sex, and refractive error. A minimum of 600 cells per control and 1200 per contact lens wearer were manually digitized from the

The use of contact lenses by USAF aviators.

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Contact lenses are an alternative method to spectacles for correcting refractive errors, but the U.S. Air Force prohibits the wearing of contact lenses by all aircrew members unless medically or optically indicated (AFR 167-3). USAFSAM has a clinical contact lens study consisting of 55 individuals

Stability of laser-assisted in situ keratomileusis (LASIK) at altitude.

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BACKGROUND The U.S. Air Force approved laser-assisted in situ keratomileusis (LASIK) for aircrew in May 2007. Relative to photorefractive keratectomy (PRK), LASIK potentially offers a more rapid return to flight status; however, there are concerns regarding corneal stability at altitude after

Risk factors associated with retinopathy of prematurity and visual alterations in infants with extremely low birth weight.

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OBJECTIVE Retinopathy of prematurity (RoP) is a retinal vascular disease and a frequent cause of blindness in infants. Our objective was to measure the frequency of RoP in infants with extremely low birth weight (ELBW, < 1,000 g) at the National Institute of Perinatology, Neonatal Intensive Care

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