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refractive errors/proline
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Inhibition of matrix metalloproteinase activity in the chick sclera and its effect on myopia development.
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OBJECTIVE
To investigate the contribution of matrix degradation in the two-layer avian sclera to the development of myopia.
METHODS
Tissue inhibitor of metalloproteinase-2 (TIMP-2) was used to inhibit chick scleral collagen degradation with (3)H-proline, a marker for this effect. Ex vivo scleral
Amblyopia induced by anisometropia without shrinkage of ocular dominance columns in human striate cortex.
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Amblyopia can be induced by opacity of the ocular media (e.g., cataract), misalignment of the ocular axes (strabismus), or unequal refractive error in the eyes (anisometropia). Experiments in monkeys have shown that early monocular eyelid suture, a model of amblyopia caused by cataract, results in
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