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rhamnocitrin/astragalus
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Effects of rhamnocitrin 4-β-D-galactopyranoside, isolated from Astragalus hamosus on toxicity models in vitro.
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BACKGROUND
Astragalus hamosus L. (Fabaceae) is used in herbal medicine as emollient, demulcent, phrodisiac, diuretic, laxative, and good for inflammation, ulcers, and leukoderma. It is useful in treating irritation of the mucous membranes, nervous affections, and catarrh.
OBJECTIVE
Rhamnocitrin
Anticancer potential of rhamnocitrin 4'-β-D-galactopyranoside against N-diethylnitrosamine-induced hepatocellular carcinoma in rats.
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The hepatoprotective activity of flavonoid rhamnocitrin 4'-β-D-galactopyranoside (RGP) obtained from leaves of Astragalus hamosus L. against N-diethylnitrosamine (DENA)-induced hepatic cancer in Wistar albino rats was evaluated. Hepatic cancer in rats was induced by single-dose intraperitoneal
Simultaneous Determination of Formononetin, Calycosin and Rhamnocitrin from Astragalus Complanatus by UHPLC-MS-MS in Rat Plasma: Application to a Pharmacokinetic Study.
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This assay provided a novel and generally applicable method to simultaneously determine formononetin, calycosin and rhamnocitrin in rat plasma based on ultra-high performance liquid chromatography with tandem mass spectrometry. A single step of protein precipitation procedure with methanol was
Four new flavonol glycosides from the leaves of Astragalus caprinus.
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Four new flavonol 3-O-glycosides were isolated from the leaves of Astragalus caprinus. Their structures were elucidated by spectroscopic methods as rhamnocitrin-3-O-[3-hydroxy-3-methylglutaroyl(1-->6)][beta-D-apiofuranosyl(1-->2)]-beta-D-galactopyranoside (1),
Flavonoids from Astragalus hamosus.
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A new flavonol glycoside 7-O-methyl-kaempferol 4'-beta-D-galactopyranoside (rhamnocitrin 4'-beta-D-galactopyranoside) (1) was isolated from the aerial parts of Astragalus hamosus. The known flavonols hyperoside (2), isoquercitrin (3) and astragalin (4) were also identified. Structures of the
Flavone and flavonol glycosides from Astragalus eremophilus and Astragalus vogelii.
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Two new rhamnocitrin glycosides (1 and 2) were isolated from the aerial parts of Astragalus vogelii, along with one known rhamnocitrin glycoside (3). Two known flavonol glycosides (4 and 5) and four known flavone derivatives (6-9) were isolated from the aerial parts of Astragalus eremophilus. Their
Identification of bioactives from Astragalus chinensis L.f. and their antioxidant, anti-inflammatory and anti-proliferative effects.
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This work was designed to obtain the valuable compounds with antioxidant, anti-proliferative and anti-inflammatory activities from Astragalus chinensis. Ethyl acetate fraction obtained from A. chinensis L.f. had significant antioxidant, anti-proliferative and anti-inflammatory activities.
[Studies on the efficacious constituents of Astragalus complanatus].
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The petroleum ether extract of Astragalus complanatus R. Br. showed activity for lowering the transaminase levels in mice. From this extract six compounds were isolated. Among them five were identified as rhamnocitrin (I), formononetin (II), stigmasterol (IV), phosphatidylethanolamine (V) and
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