ryanodine/ryania

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Physiology, Ryanodine Receptor

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A ryanodine receptor is a homotetrameric channel with a molecular mass of more than 2.2 megadaltons. It is the largest known ion channel and gets its name from one of its exogenous ligands, ryanodine, an alkaloid plant toxin from Ryania speciosa. Ryanodine receptor ion channels are embedded

Differential activating and deactivating effects of natural ryanodine congeners on the calcium release channel of sarcoplasmic reticulum: evidence for separation of effects at functionally distinct sites.

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Two novel natural ryanoids from extracts of the wood of Ryania speciosa Vahl were evaluated with sarcoplasmic reticulum (SR) vesicles for their binding affinities and their activating and deactivating effects on Ca2+ release channels. The new ryanoids, which are more polar than the known Ryania

Analysis by hplc of ryanodine and dehydroryanodine residues on fruits and in ryania powdery wood.

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A simple and rapid HPLC method to evaluate residues of the major ryanoids (ryanodine and dehydroryanodine) on three fruits (olives, apples, and pears) has been developed. The pesticides were extracted from the fruits with hexane and acetone solution (1:1, v/v). Cleanup was carried out with

Plant insecticides; ryanodine, a new alkaloid from Ryania speciosa Vahl.

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Ryanodyl 3-(pyridine-3-carboxylate): a novel ryanoid from Ryania insecticide.

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Ryanodyl 3-(pyridine-3-carboxylate) was isolated as a minor component from the wet CHCl3 extract of Ryania insecticide, and its structure was assigned by chemical and spectroscopic methods. This compound is essentially inactive compared with ryanodine for insecticidal activity against Musca

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