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sanguinarine/obesity
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2 rezilta yo
Sanguinarine non- versus re-circulation during isolated heart perfusion--a Jekyll and Hyde effect?
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OBJECTIVE
In isolated rat heart perfusion experiments, drug administration occurs via retrograde perfusion. This can be done in the non-recirculating mode (coronary effluent is discarded), or recirculating mode (coronary effluent is collected and reused). It was recently observed in our lab while
The Role of MKP-1 in Insulin-Induced Cardioprotection.
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OBJECTIVE
The mitogen-activated protein kinase phosphatases (MKPs) are a family of dual-specificity phosphatases that inactivate MAPKs by dephosphorylation. Impairment of MKP-1 expression in insulin resistance has been suggested to affect the cardioprotective properties of insulin. We hypothesized
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