sickle cell trait/lafyèv

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Coexistence of lupus nephritis and sickle cell trait, an electron microscopic assessment of renal glomerular damage: Case report of a rare association.

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Because of similarities of the musculoskeletal, central nervous system, and renal manifestations in both diseases, diagnosing systemic lupus erythematosus (SLE) in sickle cell disease (SCD) patients can be difficult to establish. Although Sickle Cell Trait (SCT) is still considered a benign form of

Coevality of Systemic Lupus Erythematosus With Sickle Cell Trait: A Not So Uncommon Entity

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The coexistence of systemic lupus erythematosus (SLE) with sickle cell trait is quite sparingly reported in literature. Here, we narrate the case of a 17-year-old girl from Eastern India with sickle cell trait who presented with acute lupus pneumonitis. The challenges to the final diagnosis of SLE

Relationships between sickle cell trait, malaria, and educational outcomes in Tanzania.

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Sickle Cell Trait (SCT) has been shown to be protective against malaria. A growing literature suggests that malaria exposure can reduce educational attainment. This study assessed the relationship and interactions between malaria, SCT and educational attainment in north-eastern Tanzania. Seven

A fatal case of acute chest syndrome in a patient with undiagnosed sickle cell trait.

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We report a fatal case of acute chest syndrome in an African-American male. The patient was hospitalized for respiratory distress, fevers, and pulmonary infiltrates after working in an attic space on a summer day. An extensive work-up failed to reveal an etiology for his respiratory failure. He died

Sickled erythrocytes in urine as a clue to the diagnosis of sickle cell trait.

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Sickled erythrocytes in patients of sickle cell trait with microscopic hematuria have rarely been reported so far. A 30-year-old female underwent delivery of a healthy full-term baby by cesarean section. However, postcesarean, she had pain in abdomen and fever, for which she was advised blood and

Is there increased fertility in adult males with the sickle cell trait?

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Different proposals have been offered to explain the polymorphism of the sickle cell hemoglobin gene. One of these proposals (Eaton and Mucha 1971) suggested that differential fertility of male subjects with the sickle cell trait contributes to the persistence and stability of the sickle cell gene

[Is the sickle-cell trait a risk factor?].

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Generally the sickle-cell trait is not regarded as a risk factor for morbidity or mortality and consequently does not entail occupational restrictions on physical activity (except for military pilots or divers). However many reports have described cases of visceral infarction, disseminated

An elevated creatine kinase in the context of influenza A infection and sickle cell trait.

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We describe the case of a 37-year-old normally fit and well man who presented to hospital with fever, lethargy and myalgia. He was found to have a creatine kinase level of over 1 million IU.l^-1. He initially underwent fluid resuscitation, but despite this his renal function declined and

Goats, germs, and fever: Are the pyrin mutations responsible for familial Mediterranean fever protective against Brucellosis?

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Mutations in the MEFV gene are highly prevalent in the Middle East and Mediterranean basin, with carrier rates of up to 1:3 in some populations. More than 50 mutations in the MEFV gene have been described. The high prevalence, multiple mutations, and geographic localization to the Middle East

[Co-inheritance of autosomal dominant polycystic kidney disease and sickle cell trait in African Americans].

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BACKGROUND Macroscopic haematuria secondary to renal cyst rupture is a frequent complication in autosomal dominant polycystic kidney disease (ADPKD). Sickle-cell disease is an autosomal recessive haemoglobinopathy that involves a qualitative anomaly of haemoglobin due to substitution of valine for

Pregnancy outcomes among Palestinian refugee women with sickle cell trait in Damascus, Syria.

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OBJECTIVE The results on pregnancy outcomes of mothers afflicted with sickle cell trait are still contradictory. This study aimed to examine the fetal and maternal outcomes among a cohort of pregnant women. METHODS This is a prospective cohort study that examined the fetal and maternal outcomes

Non hypoxia-related splenic infarct in a patient with sickle cell trait and infectious mononucleosis.

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Splenic infarction in patients with sickle cell trait is usually related to hypoxic conditions, while non-hypoxia-related infarcts are extremely rare. We report on a case of a 17-year-old male patient, living at sea level, who developed a severe left upper quadrant abdominal pain during the course

High Frequency of Blackwater Fever Among Children Presenting to Hospital With Severe Febrile Illnesses in Eastern Uganda.

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UNASSIGNED In the Fluid Expansion as a Supportive Treatment (FEAST) trial, an unexpectedly high proportion of participants from eastern Uganda presented with blackwater fever (BWF). UNASSIGNED We describe the prevalence and outcome of BWF among trial participants and compare the prevalence of 3

Sickle cell trait and fatal rhabdomyolysis in football training: a case study.

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We report the athletic, the clinical, and the pathological details of a case of fatal rhabdomyolysis during training in a college football player with sickle cell trait (SCT) who collapsed minutes after running 16 successive sprints of 100 yd each. The player, 19 yr old, African American, was

Health outcomes and services in children with sickle cell trait, sickle cell anemia, and normal hemoglobin.

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The health effects of sickle cell trait among children are unknown. We compared select health outcomes and health services utilization among children with sickle cell trait, sickle cell anemia (SCA), and normal hemoglobin. Newborn screening records were used to identify children with sickle cell

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