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tussilago pyrenaica/reductase

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Chemical Constituents of the Leaves of Tussilago farfara and their Aldose Reductase Inhibitory Activity.

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The inhibitory activity of 37 medicinal plant extracts against aldose reductase (AR) activity was evaluated. The most potent AR inhibitory activity was found in the MeOH extract of the leaves of Tussilagofarfara (Compositae). Enzyme assay-guided fractionation of the extract led to the isolation of a

Tussilagonone-induced Nrf2 pathway activation protects HepG2 cells from oxidative injury.

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Tussilagonone is a compound derived from the medicinal plant Tussilago farfara L., which is used as a traditional medicine for respiratory diseases, including asthma and pneumonia. Recent reports suggest that tussilagonone exhibits anti-inflammatory effects; however, the scope of protective
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