unsaturated fatty acid/sarcoma

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AN UNSATURATED FATTY ACID FRACTION OF PIG PANCREAS WHICH INHIBITS THE GROWTH OF CHICKEN SARCOMA.

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The inhibiting action of pancreatic tissue was found to be associated with the unsaturated fatty acid fraction. As small an amount of fatty acid as 0.1 mg. inhibited the chicken sarcoma agent contained in 0.2 cc. of a 1:60 aqueous extract of Chicken Tumor I. The unsaturated fatty acid had an acid

[The effect of unsaturated fatty acid extracted from the liver of irradiated rabbits on Yoshida sarcoma cells].

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Influence of iodine value, carbon number and oxidation on inhibitory activity of unsaturated fatty acids on Rous sarcoma virus.

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Some effects of the essential fatty acids linoleic acid and alpha-linolenic acid and of their metabolites gamma-linolenic acid, arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid, and of prostaglandins A1 and E1 on the proliferation of human osteogenic sarcoma cells in culture.

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Gamma-linolenic acid has been shown to suppress the rate of proliferation of a number of malignant cell lines in culture. To test the proposal that this was a specific prostaglandin 1- or 2-series effect, 379 batches of MG63 human osteogenic sarcoma cells were seeded in Greiner flasks and cultured

The concomitant effect of unsaturated fatty acid supplemented to medium on cellular growth and membrane fluidity of cultured cells.

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The membrane fluidity of cultured Yoshida sarcoma cells was determined under the culture condition in which various amounts of saturated and unsaturated fatty acids were supplemented to a serum-free medium containing defatted bovine serum albumin. The greater amount of unsaturated fatty acids was

Effect of cis-unsaturated fatty acids on Meth-A ascitic tumour cells in vitro and in vivo.

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Earlier studies performed both by us and by others have demonstrated that some n-3 and n-6 fatty acids can inhibit the growth of tumour cells in vitro. Though studies done with various types of oils rich in n-3 and n-6 fatty acids did show that the tumour incidence and growth can be modified, there

Long-term effect on the immune status of defined diets during the early postnatal period in the rat.

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Germ-free and conventional infant rats delivered by hysterectomy were reared artificially, using one of two diets--diet LNa (with a high saturated fatty acid content) and diet K 50 (with a high unsaturated fatty acid content). Animals reared for a short time (up to 5 days) after birth on the LNa

[Study of the molecular and cellular mechanisms of action of lipid immunomodulators].

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Within a narrow range of low concentrations (0.03-0.12 microgram/ml) polysialogangliosides containing unsaturated fatty acids in the lipid moiety of the molecule activate in vitro the proliferation of lymphocytes, synthesis of interleukin 2 and generation of highly active natural killers which are

In vivo magnetic resonance imaging and spectroscopy identifies oncolytic adenovirus responders.

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At present, it is not possible to reliably identify patients who will benefit from oncolytic virus treatments. Conventional modalities such as computed tomography (CT), which measure tumor size, are unreliable owing to inflammation-induced tumor swelling. We hypothesized that magnetic resonance

Antitumor activity of P-4055 (elaidic acid-cytarabine) compared to cytarabine in metastatic and s.c. human tumor xenograft models.

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The antineoplastic efficacy of P-4055, a 5'-elaidic acid (C18:1, unsaturated fatty acid) ester of cytarabine, a nucleoside antimetabolite frequently used in the treatment of hematological malignancies, was examined in several in vivo models for human cancer. In initial dose-finding studies in nude

Effects of fatty acid modification of ascites tumor cells on pulmonary metastasis in rat.

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Yoshida sarcoma cells were incubated with each of 4 different saturated and 17 different unsaturated fatty acid methyl and ethyl esters in order to modify the fatty acid composition of the cell membrane, and a possible correlation between the lipid fluidity of the cell membrane and the metastatic

Multicellular tumor spheroids of human uveal melanoma induce genes associated with anoikis resistance, lipogenesis, and SSXs.

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Uveal melanoma (UM) has a high propensity for metastatic spread, and approximately 40-50% of patients die of metastatic disease. Metastases can be found at the time of diagnosis but also several years after the tumor has been removed. The survival of disseminated cancer cells is known to be linked

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