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uricase/jaundice

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The estimation of serum urate by uricase/peroxidase procedures involving single point bichromatic absorbance monitoring gives inaccurate results with samples which are haemolysed, icteric or lipaemic. These inaccuracies can be greatly minimized by reducing the rate of chromogen formation and
Methods for the determination of serum urate which employ the uricase-peroxidase reaction may suffer interference from concentrations of bilirubin which can be found in relatively mild jaundice. Such concentrations of bilirubin are also frequently present in sera distributed as part of an external
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