venous insufficiency/glutathione

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A plasma oxidative stress global index in early stages of chronic venous insufficiency.

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BACKGROUND Chronic venous insufficiency (CVI) represents a social and health care problem because it affects working age populations, particularly in jobs requiring orthostasis, has no effective pharmacologic treatment, and requires surgery. Oxidative stress is present in varicose veins, but whether

The impact of smoking on clinical features of Behçet's disease patients with glutathione S-transferase polymorphisms.

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OBJECTIVE Various cancer studies have suggested that polymorphism of GSTM1 may influence the ability to detoxify chemicals in cigarette smoke. In the present study the effect of smoking on clinical features of Behçet's disease were investigated in patients having GST-M1 and/or -T1 null

Troxerutin protects the isolated perfused rat liver from a possible lipid peroxidation by coumarin.

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For more than 40 years coumarin has been successfully used in the therapy of chronic venous insufficiency (CVI). The occurrence of liver injuries is rather rare and happens predominantly when doses are administered which are significantly higher than necessary for therapeutical use. Such effects

Calcium dobesilate reduces oxidative stress in cardiac surgery.

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OBJECTIVE Calcium dobesilate (CD) is a synthetic benzene sulfonate derivative and an angioprotective agent used orally. It can be used in patients who have diabetic retinopathy or chronic venous insufficiency. The aim of this study was to investigate the effect of CD on the reduction of oxidative

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