voacamine/tabernaemontana

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Plant anticancer agents VI: Isolation of voacangine, voacamine, and epivoacorine from Tabernaemontana arborea sap.

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Fractionation of the sap of Tabernaemontana arborea, guided by cytotoxicity against the P-388 lymphocytic leukemia, yielded the known indole alkaloids voacangine, voacamine, and epivoacorine as the major cytotoxic constituents.

Antimycobacterial Activity of Alkaloids and Extracts from Tabernaemontana alba and T. arborea.

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Tuberculosis is the main cause of death from a single infectious agent. Globally, according to the World Health Organization, in 2018, there were an estimated 1.2 million tuberculosis deaths. Moreover, there is a continuous appearance of drug-resistant strains. Thus, development of new

Antimicrobially active alkaloids from Tabernaemontana chippii.

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From Tabernaemontana chippii root bark, forty-five alkaloids were isolated; thirty-four were fully characterized by means of their spectral data and/or co-tlc; eight alkaloids were new, four of them being 3-hydroxy derivatives of known dimeric voacamine type alkaloids. Most of the twenty-six known

Phytochemical investigations and evaluation of antimutagenic activity of the alcoholic extract of Glycosmis pentaphylla and Tabernaemontana coronaria by Ames test.

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Chemical investigation of root bark of Glycosmis pentaphylla and stem bark of Tabernaemontana coronaria led to the isolation of three carbazole alkaloids glycozoline, glycozolidine and methyl carbazole 3-carboxylate, two furoquinoline alkaloids skimmianine and dictamine, an acridone alkaloid

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