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vobasine/voacanga africana
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[Study on the alkaloids constituents from Voacanga africana].
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OBJECTIVE
To study the alkaloids of Voacanga africana.
METHODS
The alkaloids were isolated by normal phase silica gel and Sephadex LH-20 column chromatography. Their structures were elucidated by analysis of spectroscopic data.
RESULTS
Eight alkaloids were isolated and their structures were
Cytotoxic monoterpenoid indole alkaloids isolated from the barks of Voacanga africana Staph.
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A new monoterpenoid indole alkaloid compound (1) and six known monoterpenoid indole alkaloids compounds (2-7) were isolated from the barks of Voacanga africana Staph. The structures were established by spectral analysis as ibogamine-16-carboxylic acid,17,20-didehydro-5,6-dioxo-10-methoxy-methyl
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