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Exercise Training in Obesity-prone Black and White Women

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StatusLengkap
Sponsor
University of Alabama at Birmingham
Kolaborator
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Kata kunci

Abstrak

Overweight premenopausal Black and White women are randomized to either diet-only, diet+aerobic or diet+resistance exercise training. Diet/behavior intervention, with or without the aerobic or resistance exercise training, will be provided throughout the 18 months of study. Major outcomes will include measures of perceived and physiologic difficulty of exercise (cardiac, ventilatory, electromyographic responses to standardized exercise tasks); aerobic fitness; strength fitness; and spontaneous free-living energy expenditure (all derived from doubly labeled water). The results will provide insight into the effectiveness of, and the mechanisms by which, different types of exercise training can improve physical fitness, spontaneous engagement in physical activities of daily living and, in turn, weight-loss maintenance.

Deskripsi

Overweight premenopausal Black and White women are randomized to either diet-only, diet+aerobic or diet+resistance exercise training. Diet/behavior intervention, with or without the aerobic or resistance exercise training, will be provided throughout the 18 months of study. Major outcomes will include measures of perceived and physiologic difficulty of exercise (cardiac, ventilatory, electromyographic responses to standardized exercise tasks); aerobic fitness; strength fitness; and spontaneous free-living energy expenditure (all derived from doubly labeled water). The results will provide insight into the effectiveness of, and the mechanisms by which, different types of exercise training can improve physical fitness, spontaneous engagement in physical activities of daily living and, in turn, weight-loss maintenance.

Time of initial weight loss was defined as the time needed to reach the goal of 25 kg/m2 BMI. The women will then be evaluated one year after this time and the amount of weight gain will be determined.

tanggal

Terakhir Diverifikasi: 09/30/2017
Pertama Dikirim: 08/28/2003
Perkiraan Pendaftaran Telah Dikirim: 08/28/2003
Pertama Diposting: 08/31/2003
Pembaruan Terakhir Dikirim: 11/15/2017
Pembaruan Terakhir Diposting: 11/19/2017
Tanggal Mulai Studi Sebenarnya: 11/30/2000
Perkiraan Tanggal Penyelesaian Utama: 11/30/2007
Perkiraan Tanggal Penyelesaian Studi: 11/30/2007

Kondisi atau penyakit

Obesity

Intervensi / pengobatan

Behavioral: Diet

Behavioral: Diet plus aerobic exercise

Behavioral: Diet plus resistance exercise

Tahap

-

Kelompok Lengan

LenganIntervensi / pengobatan
Active Comparator: Diet only
Experimental: Diet plus aerobic exercise
Behavioral: Diet plus aerobic exercise
Experimental: Diet plus resistance exercise
Behavioral: Diet plus resistance exercise

Kriteria kelayakan

Usia yang Layak untuk Belajar 21 Years Untuk 21 Years
Jenis Kelamin yang Layak untuk BelajarFemale
Menerima Relawan SehatIya
Kriteria

- Normoglycemic

- BMI between 27-30

- Non smoker

- Premenopausal

- Physically untrained

- Family history of obesity

Hasil

Ukuran Hasil Utama

1. Weight loss [6 months]

2. Change in weight after initial weight loss [12 months after initial weight loss (maximum 18 months after randomization)]

Time of initial weight loss determined by days to reach BMI <= 25 (maximum 6 months)

Ukuran Hasil Sekunder

1. Insulin sensitivity [6 months post baseline]

2. Insulin sensitivity [18 months post baseline]

3. Change in visceral fat [6 months post baseline]

4. Change in visceral fat [18 months post baseline]

5. Change in cholesterol [6 months post baseline]

6. Change in cholesterol [18 months post baseline]

7. Change in triglycerides [6 months post baseline]

8. Change in triglycerides [18 months post baseline]

9. Change in resting energy expenditure [6 months post baseline]

10. Change in resting energy expenditure [18 months post baseline]

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