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Muscle Strength Evaluations in Ankylosing Spondylitis

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StatusMerekrut
Sponsor
Bezmialem Vakif University

Kata kunci

Abstrak

This study evaluates how the trunk and proximal girdle muscles are affected in male patients with ankylosing spondylitis, compared to healthy controls.

Deskripsi

Ankylosing spondylitis is a chronic, inflammatory rheumatic disease with an unclear etiology which causes back pain and affects the functionality of axial skeleton. Besides the effect upon axial skeleton, the disease also affects the peripheral joints. In most patients, tenuous affection of peripheral joints occurs however, in some others the disease causes impaired spinal mobility and articular instability. This causes proximal girdle muscles and trunk muscles of the patients to be exposed to excessively stress and in conclusion deformities develop. Maximum force generated by a muscle or muscle group directly effects the physical ability of an individual, and manual muscle dynamometers are used to directly evaluate the muscle strength. In this manner the investigators aim to evaluate trunk and proximal girdle muscles' powers in male patients with ankylosing spondylitis and analyze the correlation between muscle powers, and functionality and disease activity.

tanggal

Terakhir Diverifikasi: 05/31/2020
Pertama Dikirim: 06/14/2020
Perkiraan Pendaftaran Telah Dikirim: 06/15/2020
Pertama Diposting: 06/16/2020
Pembaruan Terakhir Dikirim: 06/17/2020
Pembaruan Terakhir Diposting: 06/17/2020
Tanggal Mulai Studi Sebenarnya: 06/17/2020
Perkiraan Tanggal Penyelesaian Utama: 09/14/2020
Perkiraan Tanggal Penyelesaian Studi: 09/14/2020

Kondisi atau penyakit

Ankylosing Spondylitis

Intervensi / pengobatan

Other: Truncal flexion-extension muscle power

Other: Truncal extension muscle power

Other: Cervical flexion muscle power

Other: Cervical extension muscle power

Other: Cervical lateral flexion muscle powers

Other: Shoulder flexion muscle power

Other: Shoulder extension muscle power

Other: Shoulder internal rotation muscle power

Other: Shoulder external rotation muscle power

Other: Shoulder abduction muscle power

Other: Hip flexion muscle power

Other: Hip extension muscle power

Other: Hip abduction muscle power

Other: Hip internal rotation muscle power

Other: Hip external rotation muscle power

Other: Ankylosing Spondylitis

Other: Ankylosing Spondylitis

Other: Ankylosing Spondylitis

Other: Ankylosing Spondylitis

Tahap

-

Kelompok Lengan

LenganIntervensi / pengobatan
Ankylosing Spondylitis
Patients with ankylosing spondylitis meeting the inclusion and exclusion criteria
Other: Ankylosing Spondylitis
This questionnaire evaluates the functionality in patients with AS. The ten questions that comprise the BASFI were chosen with input from patients with AS. The first 8 questions evaluate activities related to functional anatomical limitations due to the course of this inflammatory disease. The final 2 questions evaluate the patients' ability to cope with everyday life. A visual analogue scale (with 0 being "easy" and 10 "impossible) is used to answer the questions on the test. The final score varies between 0 and 10.
Healthy Controls
Healthy individuals meeting the exclusion criteria

Kriteria kelayakan

Usia yang Layak untuk Belajar 18 Years Untuk 18 Years
Jenis Kelamin yang Layak untuk BelajarMale
Metode pengambilan sampelNon-Probability Sample
Menerima Relawan SehatIya
Kriteria

Inclusion Criteria:

1. Having a diagnosis of ankylosing spondylitis according to Modified NewYork criteria

2. Being male

3. Aged ≥18

Exclusion Criteria:

1. Severe cardiac or pulmonary or renal disease

2. Accompanying fibromyalgia

3. Severe psychiatric disorder

4. Other disease limiting spinal, shoulder or hip range of motion

5. Myopathy, neuropathy or radiculopathy that may cause muscle weakness

6. Using high dose steroids

7. Endocrinological disorders

8. Malignancy

9. Pregnancy

Hasil

Ukuran Hasil Utama

1. Cervical muscle powers [1 day]

Cervical flexion, extension, and lateral flexion muscle powers in kilograms as assessed with handheld dynamometer.

2. Truncal muscle powers [1 day]

Truncal flexion and extension muscle powers in kilograms as assessed with handheld dynamometer.

3. Shoulder girdle muscle powers [1 day]

Shoulder flexion, extension, abduction, internal rotation, and external rotation muscle powers in kilograms as assessed with handheld dynamometer.

4. Hip girdle muscle powers [1 day]

Hip flexion, extension, abduction, internal rotation, and external rotation muscle powers in kilograms as assessed with handheld dynamometer.

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