Photodynamic Remediation of Black Stain
Kata kunci
Abstrak
Deskripsi
The standard treatment practice for black dental stain is dental prophylaxis, however this is often harmful to the enamel surface and can result in tooth sensitivity. In this study we aim to explore the application of antimicrobial photodynamic therapy (aPDT) for the treatment of adult black dental stain. aPDT has demonstrated positive results in the treatment of periodontitis.
Patients received an oral examination and the extent of black stain was scored (score 1, pigmented spots or incomplete lines parallel to the gingival margin, score 2: solid lines pigmented, readily observable and limited to the cervical third of the tooth surface, score 3: pigmentation extending beyond the cervical third). The patients' oral cavity was photographed in sextants, along with a complete picture of the jaw (lingual plane) and the maxillary arch (palatal plane). For bacterial analysis, 1mg of black plaque was collected by scraping with a plastic scaler from buccal tooth surfaces taking care to avoid unnecessary removal of enamel hydroxyapatite. The first dental prophylaxis was performed to remove the black stain.
Patients were reviewed monthly and in each visit, were photographed as previously described, and the level of pigmentation scored according to the mentioned criteria. The monthly visits were continued until the black stain score returned to the initial value. The period between the first and the last appointment was noted. At this point, each volunteer received dental prophylaxis once again, followed by the application of aPDT. Antimicrobial photodynamic therapy was applied to 31 orally healthy volunteers with black stained teeth, using the GLO home whitening device (GLO™ Science LLC, New York, USA) in 2 cycles of 8 minutes. Outcome variables were area, color and time taken to reappearance of black stain following dental prophylaxis with and without antimicrobial photodynamic therapy. Differences in bacterial composition of black stain (specifically Aggregatibacter actinomycetemcomitans, Tannerella forsythia and Porphyromonas gingivalis) were analyzed DNA extracted from plaque samples. Following the application of aPDT, patients were reviewed monthly until the black stain score returned to the initial value.
tanggal
| Terakhir Diverifikasi: | 09/30/2017 |
| Pertama Dikirim: | 10/01/2017 |
| Perkiraan Pendaftaran Telah Dikirim: | 10/09/2017 |
| Pertama Diposting: | 10/15/2017 |
| Pembaruan Terakhir Dikirim: | 10/09/2017 |
| Pembaruan Terakhir Diposting: | 10/15/2017 |
| Tanggal Mulai Studi Sebenarnya: | 05/04/2014 |
| Perkiraan Tanggal Penyelesaian Utama: | 04/29/2016 |
| Perkiraan Tanggal Penyelesaian Studi: | 04/29/2016 |
Kondisi atau penyakit
Intervensi / pengobatan
Procedure: Dental prophylaxis
Device: Dental prophylaxis + antimicrobial photodynamic therapy
Tahap
Kelompok Lengan
| Lengan | Intervensi / pengobatan |
|---|---|
| Active Comparator: Dental Prophylaxis Standard dental prophylaxis | |
| Active Comparator: Dental prophylaxis + antimicrobial photodynamic therapy Dental prophylaxis + aPDT | Device: Dental prophylaxis + antimicrobial photodynamic therapy Dental prophylaxis using American Dental Association, Code on Dental Procedures and Nomenclature (CDT) CDT code D1110 followed by two 8-minute irradiation cycles using GLO Brilliant home use whitening device (GLO ™ Science LLC, New York, USA). |
Kriteria kelayakan
| Usia yang Layak untuk Belajar | 18 Years Untuk 18 Years |
| Jenis Kelamin yang Layak untuk Belajar | All |
| Menerima Relawan Sehat | Iya |
| Kriteria | Inclusion Criteria: - Volunteers with black stained (plaque on) teeth Exclusion Criteria: - Children - Pregnant women - Volunteers having completed antibiotic therapy during 15 days prior to the start of the study |
Hasil
Ukuran Hasil Utama
1. Restoration period [The period of time required for the restoration of the black stain to pre-cleaning levels will be determined by measurements carried out during Weeks 18-24, post-application of each treatment arm]
Ukuran Hasil Sekunder
1. Black stain color [The depth of color of the black stain will be measured at Week 20 following the application of each treatment arm]
2. Black stain area [Area covered by the black stain will be carried out at Week 20 following the application of each treatment arm]
3. Microbial composition [Black plaque sampling will be carried out at Week 0, followed by a second sampling at Week 20, following the application of each treatment arm, in accordance with the reappearance rate of the black stain in each study volunteer]
