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Molecules 2010-Mar

Chemical composition and biological properties of Rhododendron anthopogon essential oil.

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Gabbriella Innocenti
Stefano Dall'Acqua
Giuditta Scialino
Elena Banfi
Silvio Sosa
Khilendra Gurung
Mariagnese Barbera
Maria Carrara

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The essential oil of Rhododendron anthopogon was investigated by GC-MS, and seventeen compounds (representing approximately 98% of the oil) were identified. The major components of the aerial parts of the oil were the monoterpenes alpha-pinene, beta-pinene, limonene and the sesquiterpene delta-cadinene. Biological studies revealed a weak topical anti-inflammatory activity; a significant killing effect against some Gram-positive reference strains: Staphylococcus aureus, Enterococcusfecalis, Bacillus subtilis was measured; Mycobacterium tuberculosis reference strain and a clinical isolate of Candida, C. pseudotropicalis were killed by as low as 0.04% (v/v) essential oil. Moreover, the oil was able to reduce cancer cell growth independently of the cell line and the treatment protocols used.

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