Planta Medica 1995-Dec
Larvicidal constituents of Melantheria albinervia.
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Bioactivity-guided fractionation has led to the isolation of two larvicidal diterpenes, active against the yellow fever-transmitting mosquito Aedes aegypti, from a dichloromethane root extract of Melantheria albinervia (Asteraceae), a plant from Zimbabwe. These diterpenes were identified as ent-kaur-16-en-19-oic acid and 9(11),16-kauradien-19-oic acid. The diterpenes were also weakly active against Bacillus subtilis.
