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3 butylphthalide/ligusticum chuanxiong
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[Studies on chemical constituents of rhizomes of Ligusticum chuanxiong].
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OBJECTIVE
To study chemical constitutents of the rhizomes of Ligusticum chuanxiong.
METHODS
The rhizomes of L. chuanxiong were extracted with water to afford a water extract which was participated between H2O and EtOAc, n-BuOH, successively. The compounds were isolatedand purified by column
Identification and comparison of metabolites after oral administration of essential oil of Ligusticum chuanxiong or its major constituent ligustilide in rats.
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The rhizome of Ligusticum chuanxiong Hort. is a well-known traditional Chinese medicinal herb that is widely used to treat various vascular diseases. The aims of this study were to identify and compare the metabolites in rats after the oral administration of the essential oil of Ligusticum
Simultaneous analysis of seventeen chemical ingredients of Ligusticum chuanxiong by on-line high performance liquid chromatography-diode array detector-mass spectrometry.
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An on-line high performance liquid chromatography (HPLC)-diode array detector (DAD)-mass spectrometry (MS) analytical method has been developed to simultaneously separate and identify seventeen main constituents of Chuanxiong ( Ligusticum chuanxiong Hort.), a traditional Chinese medicinal herb. In
[Studies on chemical constituents of the rhizomae of Ligusticum chuanxiong].
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OBJECTIVE
To study the chemical constituents of Ligusticum chuanxiong.
METHODS
The constituents were separated and purified by column chromatography with silica gel and ODS, and identified by NMR, MS spectral data.
RESULTS
Eight compounds were isolated and identified as Ligustilide(I),
GC-MS fingerprints for discrimination of Ligusticum chuanxiong from Angelica.
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A GC-MS fingerprinting technique based on the essential oil components has been developed for the discrimination of chuanxiong against Chinese Angelica (Angelica sinensis (Oliv.) Diels) or other herbs with similar compositions. The analytical performance of four different extraction methods for the
Ultra-high performance liquid chromatography with tandem mass spectrometry method for the simultaneous quantitation of five phthalides in rat plasma: Application to a comparative pharmacokinetic study of Huo Luo Xiao Ling Dan and herb-pair extract.
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A fast, sensitive, and reliable ultra-high performance liquid chromatography with tandem mass spectrometry method has been developed and validated for the simultaneous quantitation and pharmacokinetic study of five phthalides (senkyunolide A, ligustilide, butylidenephthalide, 3-butylphthalide, and
Metabolic profiling of senkyunolide A and identification of the metabolite in hepatocytes by ultra-high performance liquid chromatography combined with diode array detector and high resolution mass spectrometry
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Rationale: Senkyunolide A is one of the bioactive constituents originally isolated from Ligusticum chuanxiong Hort. To better understand the action of this constituent, it is necessary to study the metabolic profiles in different
Identification and determination of the major constituents in Traditional Chinese Medicinal formula Danggui-Shaoyao-San by HPLC-DAD-ESI-MS/MS.
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Danggui-Shaoyao-San (DSS), a famous traditional Chinese medicine formula consisting of six herbal medicines (Paeonia lactiflora, Angelica sinensis, Ligusticum chuanxiong, Poria cocos, Atractylodis macrocephalae and Rhizoma Alismatis), has been used as a classical gynecological remedy in China for
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