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aframomum melegueta/antiinflamasi
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Anti-inflammatory activity of grains of paradise (Aframomum melegueta Schum) extract.
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The ethanolic extract of grains of paradise (Aframomum melegueta Schum, Zingiberaceae) has been evaluated for inhibitory activity on cyclooxygenase-2 (COX-2) enzyme, in vivo for the anti-inflammatory activity and expression of several pro-inflammatory genes. Bioactivity-guided fractionation showed
Toxicological evaluation of grains of paradise (Aframomum melegueta) [Roscoe] K. Schum.
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BACKGROUND
Grains of Paradise (Aframomum melegueta [Roscoe] K. Schum.) seeds are used in West Africa as a remedy for variety of ailments such as stomach ache, snakebite, diarrhea and they have reported anti-inflammatory properties. Additionally, the seeds contain gingerols and related compounds that
Anti-Helicobacter pylori and antiulcerogenic activity of Aframomum pruinosum seeds on indomethacin-induced gastric ulcer in rats.
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BACKGROUND
Peptic ulcer is one of the most common diseases affecting mankind. Although there are many products used for its treatment, most of these products produce severe adverse reactions requiring the search for novel compounds. Some Afromomum species are used traditionally to cure acute
Lipoxygenase inhibitors in the seeds of Aframomum danielli K. Schum (Zingiberaceae).
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Alcohol and petrol extracts of the seeds of Aframomum danielli inhibit the soya 5-lipoxygenase enzyme and thus may show antiinflammatory activity. Compounds isolated from the active fractions were shown to be long chain polyprenyl benzoquinone derivatives. Phytylplastoquinone was isolated from the
Thirty days oral Aframomum melegueta extract elicited analgesic effect but influenced cytochrome p4501BI, cardiac troponin T, testicular alfa-fetoprotein and other biomarkers in rats
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Ethnopharmacological relevance: Pain is the commonest symptom of a disease and the percentage of persons manifesting one form of pain is growing globally. Aframomum melegueta (AM) is commonly used by traditional doctors as medication for
Some Nigerian plants of dermatologic importance.
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BACKGROUND
According to the World Health Organization (WHO), 80% of the world's population uses medicinal plants in the treatment of diseases and, in African countries, this rate is much higher. In recent years, however, medicinal plants have represented a primary health source for the
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