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Two new constituents from the leaves of magnolia coco
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A new amide, magnolamide (1), and a new lignan, magnolone (2), whose structures were determined on the basis of spectral analysis, were found in the leaves of Magnolia coco. Eleven known compounds (episesamin, sesamin, magnolol, fargesin, aschantin, epieudesmin, syringaresinol,
[Biologically active lignins from Magnolia biondii Pamp].
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Guided by PAF induced platelet aggregation, six active lignins were isolated from the flower buds of Magnolia biondii and identified as fargesin, demethoxyaschantin, aschantin, pinoresinol dimethyl ether, magnolin, lirioresinol-B dimethyl ether. The 13CNMR and CD data were reported and the
[Lignans from flower buds of Magnolia biondii].
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The present study aims to investigate the lignans from the flower buds of Magnolia biondii. The isolation and purification of the compounds were performed by column chromatographies on Diaion HP-20, silica gel, and Sephadex LH-20, combined with semi-preparative HPLC. Their structures were elucidated
Suppression of inducible nitric oxide synthase expression by furfuran lignans from flower buds of Magnolia fargesii in BV-2 microglial cells.
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Activated microglia produces diverse neurotoxic factors such as nitric oxide (NO) and tumor necrosis factor-alpha that serve as apoptotic inducers resulting in various neurodegenerative diseases. The inhibition of microglia-derived NO production by inducible nitric oxide synthase (iNOS) has been
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