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A Proof-of-Concept Trial on the Effect of Ketamine on Fatigue

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Purpose: The purpose of the study is to investigate the anti-fatigue effects of ketamine in individuals with chronic illness. Background: Although the underlying mechanisms of fatigue have been studied in several disease conditions, the etiology, mechanisms, and risk factors remain elusive and this

ROOM-LIGHT: Effect of a Dynamic Lighting System in Depressed Inpatients

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The participant population: depression is a common disorder with a prevalence of about 150,000 in Denmark. According to WHO depression is a leading cause of disability worldwide and is a major contributor to the global burden of disease. Society suffers large direct and indirect losses in terms of

Effects of Virtual Reality on Pre-Operative Anxiety and Induction of Anesthesia in Children and Adolescents

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There are approximately five million pediatric surgeries performed in the United States every year, and approximately 50% of pediatric patients experience significant stress and anxiety before their surgery. High anxiety can result in increased postoperative pain, increased analgesic consumption,

Virtual Reality for Osteoarthritis Knee Pain Pilot

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The primary objective of this study is to examine the feasibility and acceptability of a new virtual reality (VR) protocol that uses an iPod Touch/iPhone (or similar smartphone) to deliver virtual reality (VR). The secondary objective of this study is to gather preliminary data on the efficacy and

Visual Discomfort and Reading

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Wilkins et al (1980) found that paroxysmal activity in photosensitive epileptic patients can be triggered by binocular viewing of a large repetitive striped pattern with a spatial frequency of 1-4 cycles deg-1, a contrast of 10% or more, and a duty cycle of 50%. Sensitivity to this visual pattern

Research Study of Treatment for Winter Depression With Different Colors of Light

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Studies report as many as 1 out of every 5 Americans is affected by mild to severe Seasonal Affective Disorder (SAD, winter depression). Although the exact cause of this condition is unknown, bright light has proven to be an effective therapeutic treatment for many people with SAD. The light sources

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