atractylodin/lancea

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A new 9-nor-atractylodin from Atractylodes lancea and the antibacterial activity of the atractylodin derivatives.

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A new compound, namely, 9-nor-atractylodin (1) and one known atractylodin (2) were isolated from the rhizomes of Atractylodes lancea. The structural modifications of atractylodin were carried out and a series of atractylodin derivatives (3-10) were obtained. The antibacterial activities of 1-10 were

[Effect of endophytic fungal elicitors on growth and atractylodin accumulation of cell suspension cultures of Atractylodes lancea].

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OBJECTIVE To investigate the effects of endophytic fungal elicitors on the growth and atractylodin accumulation of cell suspension cultures of Atractylodes lancea. METHODS The endophytic fungal elicitors were added to the medium with different concentrations and culture period. Their effects on

A comparative study on essential oil components of wild and cultivated Atractylodes lancea and A. chinensis.

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To clarify the variation in the pharmacologically active components of the essential oil contained in the rhizomes of Atractylodes lancea and A. chinensis growing in China, we transplanted the rhizomes of the wild plants from 18 populations, including A. koreana, in the same experimental field.

Genetic and environmental factors influencing the contents of essential oil compounds in Atractylodes lancea.

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Rhizomes of Atractylodes lancea are used in traditional Japanese medicine (Kampo) and Chinese medicine to treat numerous diseases and disorders because they contain many pharmacologically active compounds. The major active compounds in A. lancea are essential oil compounds such as β-eudesmol,

Lipase inhibition and antiobesity effect of Atractylodes lancea.

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The ethanol extract of Atractylodes lancea rhizome displayed significant lipase inhibition with an IC50 value of 9.06 µg/mL in a human pancreatic lipase assay from high-throughput screening. Bioassay-guided isolation led to the identification of one new polyacetylene,

Atractylodes lancea autotetraploids induced by colchicine treatment of shoot cultures.

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Two strains of autotetraploid plants of Atractylodes lancea DC. (Compositae) were raised from the in vitro colchicine-treated shoot cultures, and field trials were performed to evaluate their growth and the amount of essential oil components in the rhizome in comparison with the corresponding

Further phenols and polyacetylenes from the rhizomes of Atractylodes lancea and their anti-inflammatory activity.

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From the rhizomes of Atractylodes lancea, 2-[(2'E)-3',7'-dimethyl-2',6'-octadienyl]-4-methoxy-6-methylphenol (1) was isolated as a new natural product. The compound showed strong inhibitory effects on 5-lipoxygenase (5-LOX) and cyclooxygenase-1 (COX-1), but exhibited only weak antioxidative

[Simultaneous determination of atractylone, hinesol, beta-eudesmol, atrctylodin in Atractylodes lancea and hierarchical cluster analysis].

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OBJECTIVE To develop a GC method for simultaneous determination of 4 compounds (atractylone, hinesol, beta-eudesmol and atractylodin) in Atractylodes lancea. METHODS A HP-1 capillary column (0.25 mm x 30 m, 0.25 microm) was used. The detector was FID:Inlet temperature was 250 degrees C. The detector

[The naphtha composing characteristics of geoherbs of Atractylodes lancea].

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OBJECTIVE To find the chemical diversity and characteristics of A. lancea on two levels--individuals and populations, and to discover the chemical essentials for forming geoherbs. METHODS 47 rhizomes of A. lancea were collected in 7 populations, and 6 naphtha components (1. elemol, 2. hinesol, 3.

[Effects of Lime on Seedling Growth,Yield and Volatile Constituents of Atractylodes lancea].

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OBJECTIVE To investigate the effects of different amounts of lime on yield and quality of Atractylodes lancea, and to provide reference for the herb growing site soil improvement and self-poisoning ease. METHODS Add different gradients of lime, and then measure their growth targets, yield and four

Bioactive constituents isolated from Atractylodes lancea (Thunb.) DC. rhizome exhibit synergistic effect against cholangiocarcinoma cell.

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Cholangiocarcinoma (CCA) is the primary type of bile duct cancer with high morbidity and mortality, particularly in patients with advanced-stage disease. Treatment of CCA remains unsatisfactory due to the lack of sensitive and specific diagnostic tool for early detection as well as

Regionalization of Chinese Material Medical Quality Based on Maximum Entropy Model: A case study of Atractylodes lancea.

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Atractylodes is an East-Asiatic endemic genera that distributed in China, Japan and Russian Far Eastern. As an important resource of medicinal plant, atractylodes has long been used as herbal medicine. To example the significant features in its trueborn quality and geographical distribution, we

Botanical and chemical evaluation of Atractylodes lancea plants propagated in vitro and by division of the rhizome.

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A single plant of Atractylodes lancea, a perennial herb of Asteraceae, was propagated in vitro by shoot culture from floral buds and shoot tips. The reproduced plants were then grown under field conditions for up to four years and their botanical and chemical characteristics were compared to those

Insecticidal and repellant activities of polyacetylenes and lactones derived from Atractylodes lancea rhizomes.

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During a screening program for new agrochemicals from Chinese medicinal herbs and local wild plants, the petroleum ether (PE) extract of Atractylodes lancea (Thunb.) rhizomes was found to possess repellent and contact activities against Tribolium castaneum adults. Bioactivity-directed

Effect of the rhizomes of Atractylodes lancea and its constituents on the delay of gastric emptying.

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The effect of rhizomes of Atractylodes lancea on gastric disorders, in particular, the delay in gastric emptying induced by N(G)-nitro-L-arginine in rats, was investigated. Intragastric treatment with an aqueous extract (250 mg/kg) and its lipophilic fractions (4 mg/kg) significantly improved

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