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beta d galactose/leukemia
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[The expression of P-glycoprotein in leukemia P388 cells with induced doxorubicin resistance].
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beta-D-galactose-containing glycoproteins were prepared from cells P-388 leukemia and from P-388 leukemia cells with induced resistance to doxorubicin. It was shown by HPLC method that plasma membranes from resistant cells contain 4-4.5% P-glycoproteins and plasma membranes from sensitive cells
Lectinocytochemical detection of apoptotic murine leukemia L1210 cells.
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BACKGROUND
Various cytomorphologic and biochemical markers of apoptosis are found in different compartments (plasma membrane, cytoplasm, nucleus, and mitochondria) of target cells. Although the plasma membrane is an easily accessible cellular compartment, relatively little is known about its changes
Cytochemical study of role of alpha-d-mannose- and beta-d-galactose-containing glycoproteins in apoptosis.
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Recently, we found increased levels of alpha-d-mannose- and beta-d-galactose-containing glycoproteins in plasma membrane of the apoptotic murine leukemia L1210 cells (Bilyy & Stoika 2003). That indicator was suggested to be a novel marker of apoptosis in L1210 cells. The aim of our present work was
Synthesis of a glycopolymeric Pt(II) carrier and its induction of apoptosis in resistant cancer cells.
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Post-polymerization modification of a poly(pentafluorostyryl) backbone with β-d-galactose and a terpyridine platinum complex yields a well-defined material that represents the first example of a metal-conjugated glycopolymer. It reveals anti-proliferative activity, no detectable necrotic
In vivo expression and characteristics of novel alpha-D-mannose-rich glycoprotein markers of apoptotic cells.
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We recently established that an increased expression of alpha-D-mannose (Man)- and beta-D-galactose-rich plasma membrane glycoproteins (GPs) is characteristic for apoptotic cells in vitro [Bilyy, R.O., Stoika, R.S., 2003. Lectinocytochemical detection of apoptotic murine leukemia L1210 cells.
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