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Epidemiology of Coronary Heart Disease in Blacks

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BACKGROUND: Ample data now exist to dispel the prevailing clinical impression that coronary heart disease (CHD) occurs infrequently in United States Blacks. It is well known that CHD is the leading cause of death among United States Blacks. Among patients with acute myocardial infarction who often

Clinical Course of Coronary Artery Disease Among Blacks

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BACKGROUND: The Black population has age-specific all causes mortality rates among adults which are up to 3.5 times higher than for whites. There remains a pressing need to improve detection and treatment of coronary artery disease among Blacks in an attempt to reduce these unfavorable racial

A Program to Increase Physical Activity Among Blacks

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The intervention will be conducted in 24 churches. Participating churches will be recruited from the list of churches that participated in the Health Ministry Institute, a program including ~40 minority-serving churches in Forsyth County conducted by Dr. Whitt-Glover 2 years ago. We will enroll

Charleston Heart Study - Predictors of Coronary Disease in Blacks

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BACKGROUND: Coronary heart disease is the leading cause of death among United States Blacks, where coronary heart disease mortality rates are among the highest in the world. There has been a marked decline in coronary heart disease mortality among Blacks in the United States including South Carolina

Carotid Web Associated With Cerebral Infarctions

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Carotid web lesions associated with cerebral infarctions are a relatively rare and largely unknown disease. However, carotid web lesions are associated with severe infarction involving the functional and vital prognosis of patients. The high rate of recurrence should lead to an identification of the

Psychophysiology of Cardiovascular Reactivity

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BACKGROUND: Blacks in the United States have a much greater prevalence of essential hypertension than whites. The prevalence of hypertension for adults aged 18-74 has been estimated at 15.7 percent for white women, 18.5 percent for white men, 27.8 percent for Black men and 28.6 percent for Black

Tea's Effect on Atherosclerosis Pilot Study (TEA Study)

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Tea is widely thought to have health benefits, particularly on cardiovascular disease (CVD). The investigator's group recently found that intake of 2 or more cups of tea per day was associated with a 44% lower long-term mortality rate than abstention from tea among 1900 patients hospitalized with

Stroke Incidence and Risk Factors in a Tri-ethnic Region

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Stroke remains a major public health problem with a disproportionate impact on blacks and Hispanics. Studies in Northern Manhattan have demonstrated that blacks and Hispanics have a greater stroke incidence and more frequently have small vessel and intracranial atherosclerotic stroke than

Hypertension Detection and Follow-up Program (HDFP)

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BACKGROUND: Published data from the Veterans Administration Cooperative Study of Hypertension demonstrated that reduction in morbidity and mortality could be attained by treating men with fixed diastolic blood pressure over 105 mm Hg. Similar trends occurred for those with fixed diastolic blood

Telehealth Management in HF Disparity Patients

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Disparities in cardiovascular disease have received particular focus, as cardiovascular disease is a major contributor to differences in morbidity and mortality between blacks and whites. African Americans, for example, are hospitalized for chronic heart failure (CHF) at a higher rate than whites

Culturally-Tailored Approach to Improve Medication Use in Patients With Heart Attacks

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The lipid-specific and pleiotropic benefits of statin therapy, and secondary prevention of coronary artery disease (CAD) mortality have been demonstrated. Statin therapy in particular is underutilized in both white and Black American populations who have CAD and who do not have access to therapy or

Evans County Studies

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BACKGROUND: The Evans County Studies were initiated as a result of a request from the National Heart Institute in the late 1950's to develop epidemiological studies in areas where significant racial or ethnic differences in cardiovascular disease rates had been observed and where a stable population

Children's Activity and Nutrition III

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BACKGROUND: Children's Activity and Nutrition III was originally part of the Institute-initiated Studies of Children's Activity and Nutrition (SCAN), first funded in 1985. Children's Activity and Nutrition III was renewed in 1992 as a stand-alone project with a focus on assessment of the development

A Trial of Alirocumab and Plaque Regression in Peripheral Arterial Disease

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PAD is characterized by lower limb arterial obstruction due to atherosclerosis. There are over 8.5 million people with PAD in the U.S. Recent data in a general population over 40 demonstrated an incidence of PAD defined by ankle brachial index (ABI) of 4.3%. Another study of over 3000 patients, mean

Effects of Neighborhood SES on Coronary Heart Disease Burden in Communities - Ancillary to ARIC

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BACKGROUND: Despite strong decreases in coronary heart disease (CHD) mortality over past decades, there is evidence that racial and socioeconomic disparities in CHD mortality are increasing. CHD surveillance efforts that examine trends within these population subgroups are an important first step in
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