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Millettia nitida var. hirsutissima is a Chinese herbal medicine used for the treatment of gynecological diseases. An HPLC/DAD/ESI-MS n method was established for the rapid separation and characterization of bioactive flavonoids in M. nitida var. hirsutissima. A total of 32 flavonoids were detected,
Two new compounds, (2R)-7,3'-dihydroxy-6,4'-methoxyflavan (1) and (3R)-7,4'-dihydroxy-2'-methoxyisoflavan (2), along with 12 known flavonoids (3-14), were isolated from the vine stems of Millettia nitida var. hirsutissima. The structures of the isolated compounds were elucidated based on
From the stems of Millettia nitida var. hirsutissima, three new isoflavone glycosides, formononetin 7-O-beta-D-(6''-ethylmalonyl)-glucopyranoside (1, hirsutissimiside A), 5-O-methyl genistein 7-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (3, hirsutissimiside B), retusin
OBJECTIVE
To separate effective constituents from Millettia nitida var. hirsutissima.
METHODS
Compounds were isolated by chromatography methods, structures were identified by spectroscopic means.
RESULTS
Eight flavonoids (1-8) and two triterpenes (9-10) were isolated from this plant. They were