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coccidiosis/phosphatase
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[Synthesis of glucose-6-phosphatase in small intestine mucosa during experimental coccidiosis in suckling piglets].
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Glucoso-6-phosphatase activity (EC. 3.1.3.9.) was evaluated microdensitometrically in the small intestine mucosa of 19 conventional piglets infected with Eimeria debliecki coccidium oocysts (infection dose of 200,000 oocysts) on day 1 after delivery (DAD). The synthesis of the observed hydrolase was
[Histochemistry of acid phosphatase in small intestine mucosa in experimental coccidiosis in suckling piglets].
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The activity of acid phosphatase (phosphohydrolase of orthophosphate monoesters; EC. 3.1.3.2) was evaluated densitometrically in the mucosa of duodenum, jejunum and ileum of 22 conventional piglets which were experimentally infected by oocysts of the coccidiae Isospora suis (infection dose of
[Changes in the activity of intestinal phosphatases during experimental coccidiosis of chickens (E. tenella, E. mitis)].
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[Histochemistry of nucleoside phosphatases and phosphoglucomutase in the small intestine during coccidiosis in piglets].
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The first day after birth, 22 conventional piglets were experimentally infected with the oocysts of the coccidia of I. suis (infection dose 200,000 oocysts). The activity of 5-nucleotidase (5-ribonucleotide phosphohydrolase, EC.3.1.3.5) and phosphoglucomutase (alpha-D-glucoso-1-phosphate
The antibiotic robenidine exhibits guanabenz-like cytoprotective properties by a mechanism independent of protein phosphatase PP1:PPP1R15A.
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The aminoguanidine compound robenidine is widely used as an antibiotic for the control of coccidiosis, a protozoal infection in poultry and rabbits. Interestingly, robenidine is structurally similar to guanabenz (analogs), which are currently undergoing clinical trials as cytoprotective agents for
Hematological and serum biochemical analyses in experimental caprine coccidiosis.
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In order to provide information on hematological and biochemical changes in Eimeria arloingi infection, eighteen newborn kids were allocated to three equal groups. Two groups, A and B were inoculated with a single dose of 1 × 10(3) and 1 × 10(5) sporulated oocysts of E. arloingi, respectively. The
[Etiopathogenesis and epizootiology of coccidiosis in rabbits].
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Studies were carried out on the etiology and epizootiology of rabbit coccidiosis. Three experimental groups of rabbits were infected with intestinal, liver, and mixed intestinal and liver coccidia. The shedding of oocysts and the clinical course of the disease were followed up, with description of
A novel serine/threonine protein phosphatase type 5 from second-generation merozoite of Eimeria tenella is associated with diclazuril-induced apoptosis.
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Screening the anticoccidial drug targets is very important for developing novel drugs and revealing the molecular basis of drug resistance in coccidia. Due to high effectivity and safety, diclazuril was used widely in the poultry industry. To assess the roles of the serine/threonine protein
Molecular characterization of serine/threonine protein phosphatase of Eimeria tenella.
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Avian coccidiosis is a widespread and economically significant poultry disease caused by several Eimeria species, including Eimeria tenella. Previously, E. tenella serine/threonine protein phosphatase (EtSTP) was found to be differentially expressed in drug-sensitive (DS) and resistant strains using
Chemotherapy and chemoprophylaxis of hepatic coccidiosis with sulphadimethoxine and pyrimethamine.
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The activity of a mixture of sulphadimethoxine and pyrimethamine (10:3) as prophylactic medication and prophylactic and therapeutic medication was studied in rabbits experimentally infected with Eimeria stiedai. The haematocrit index (packed cell volume) and haemoglobin levels were studied for
Hematological and serum biochemical analyses in experimental caprine besnoitiosis.
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This study was undertaken to investigate the hematological and biochemical changes in experimentally infected goats with Besnoitia caprae from the time of infection till 360 days post-infection (PI). Six male goats were inoculated subcutaneously with 13 × 10(7) bradyzoites of B. caprae, and blood
Evaluation of plasma chemistry and haematological studies on chickens infected with Eimeria tenella and E acervulina.
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Plasma chemistry and haematological studies were conducted on chickens with coccidiosis. Male White Leghorn chickens, of two weeks old, were inoculated with 5 x 10(4) Eimeria tenella sporulated oocysts or with 1 x 10(6) E acervulina sporulated oocysts. Blood samples were taken four, seven and 11
[Alteration of enzyme activities in serum of Eimeria stiedai infected rabbits (author's transl)].
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In experimental investigations on Eimeria stiedai infected rabbits, serum enzymatic studies have been carried out in correlation with the examination of parasitological and pathological parameters. The rabbits were orally infected with a single dose of either 100,000 or 250,000 sporulated oocysts.
Profiling of jejunum inflammatory gene expression during murine eimeriosis.
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To understand the host-parasite relationship during coccidiosis it is necessary to identify the transcriptional profile of the local host. In this study, gene profiling in the mouse jejunum due to infection with Eimeria papillata was investigated using Agilent microarray technology. On day 5
Changes in the blood composition of calves during experimental and natural infections with Eimeria alabamensis.
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Two trials were carried out to assess the changes in blood composition of calves infected either experimentally or naturally with Eimeria alabamensis. In the first, 12 calves were dosed orally with 10 to 400 million sporulated oocysts and compared with three control calves. The second trial used
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