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The relationship between inflammatory markers and post stroke cognitive impairment.

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OBJECTIVE To determine whether there is a relationship between inflammatory markers (serum C-reactive protein (CRP) and cytokines) and post stroke cognitive impairment (PSCI). METHODS This was a cross-sectional observational study. Patients were recruited from 4 sources: (1) the acute stroke unit of

Chronic inflammation - inflammaging - in the ageing cochlea: A novel target for future presbycusis therapy.

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Chronic, low-grade inflammation, or inflammaging, is a crucial contributor to various age-related pathologies and natural processes in aging tissue, including the nervous system. Over the past two decades, much effort has been done to understand the mechanisms of inflammaging in disease models such

Incidence and clinical features of acute inflammatory polyradiculoneuropathy in Lombardy, Italy, 1996.

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OBJECTIVE To assess the annual incidence of typical Guillain-Barré syndrome (GBS) and its main variants (atypical GBS) in a well-defined population from a large area. METHODS A population-based prospective survey of GBS was undertaken during the calendar year 1996 in Lombardy, Italy (population
Gestational exposure to PM2.5 is a worldwide environmental issue associated with long-lasting behavior abnormalities and neurodevelopmental impairments in the hippocampus of offspring. PM2.5 may induce hippocampus injury and lead to autism-like behavior such as social
Background: Developmental disorders are associated with microglial dysfunction. Oral administration of lipopolysaccharide derived from Pantoea agglomerans bacteria (LPSp) leads to normalization of phagocytic activity of microglia and

Squamous cell carcinoma of the external auditory canal.

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Squamous cell carcinoma of the external auditory canal is an unusual head and neck malignancy. It may occur in an ear in which there had previously been chronic inflammation, either in the external canal or middle ear. However, in most cases the etiology of the cancer is unclear. Treatment

Does caffeine intake protect from Alzheimer's disease?

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Caffeine is the most widely consumed behaviourally active substance in the western world. Neuroprotective effects of caffeine in low doses, chronically administered, have been shown in different experimental models. If caffeine intake could protect against neurodegeneration in Alzheimer's disease

Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial.

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BACKGROUND This study reports the findings of the first large-scale Phase III investigator-driven clinical trial to slow the rate of cognitive decline in Alzheimer disease with a dihydropyridine (DHP) calcium channel blocker, nilvadipine. Nilvadipine, licensed to treat hypertension, reduces amyloid

CSF filtration is an effective treatment of Guillain-Barré syndrome: a randomized clinical trial.

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OBJECTIVE To compare CSF filtration (CSFF) and plasma exchange (PE) in the treatment of patients with Guillain-Barré syndrome (GBS). METHODS In a prospective controlled clinical trial, 37 patients with acute GBS were randomized to receive either CSFF or PE. Inclusion criteria were fulfillment of
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