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congenital hypothyroidism/phosphatase

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Distinguishing hypophosphatasia from cretinism by means of alkaline phosphatase stain of skin biopsy.

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Congenital Hypothyroidism and Bone Remodeling Cycle.

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OBJECTIVE The present study aimed to evaluate the biochemical markers of bone turnover in children with congenital hypothyroidism during the course of treatment as compared to healthy children selected as controls. METHODS The study included 31 children with congenital hypothyroidism and 29 healthy

Bone mineral density and metabolism in children with congenital hypothyroidism after prolonged L-thyroxine therapy.

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The effect of long-term L-thyroxine (LT4) replacement therapy on bone mineral density and on biochemical markers of bone turnover were studied in children with congenital hypothyroidism (CH). Forty-four children and adolescents (mean age 8.5 +/- 3.5 years) with primary CH who began LT4 replacement

Significance of low serum alkaline phosphatase activity in a predominantly adult male population.

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The causes for low serum alkaline phosphatase (ALP) activity (reference range 30-115 U/L) in a large Veterans Medical Center were reviewed. Of 69,864 ALP determinations made over a 4-year period, 130 were low (< 30 U/L, 0.19%), representing 88 individual patients. Of these, 83 (primarily men, 96%)

Prevention of Vitamin D deficiency in infancy: daily 400 IU vitamin D is sufficient.

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CONCLUSIONS AIM-OBJECTIVE: Vitamin D deficiency and rickets in developing countries continues to be a major health problem. Additionally, the increase of cases of rickets in children of some ethnic groups in the United States and European countries has provided this issue to be updated. Obviously,

The effect of thyroid functions on osteopenia of prematurity in preterm infants.

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Background It is known that thyroid hormones have effects on bone development. In particular, the effect of thyroid hormones on osteopenia of prematurity (OOP) has not been examined in preterm infants. Our study aimed to examine the relationship between OOP and congenital hypothyroidism (CH) in

Oxidants in Physiological Processes

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A number of diseases and conditions have been associated with prolonged or persistent exposure to non-physiological levels of reactive oxygen species (ROS). Similarly, ROS underproduction due to loss-of-function mutations in superoxide or hydrogen peroxide (H2O2)-generating
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