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corydalis govaniana/iskemia
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Corydalis yanhusuo rhizoma extract reduces infarct size and improves heart function during myocardial ischemia/reperfusion by inhibiting apoptosis in rats.
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The aim of the present investigation was to evaluate the effect of an extract from Corydalis yanhusuo W.T., a Chinese herbal medicine, on ischemia/reperfusion (I/R) injury and to determine the mechanism(s) involved. In rats, the left anterior descending (LAD) coronary artery was occluded for 30 min
[Studies on chemical constituents in the anti-myocardial ischemia effective fraction of Corydalis yanhusuo].
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OBJECTIVE
To study the chemical constituents in the anti-myocardial ischemia effective fraction of Corydalis yanhusuo.
METHODS
Compounds were isolated and purified by a macroporous resin, Sephadex LH-20, ODS column chromatography, and prepared TLC. Their structures were identified by spectral
Effect of Rhizoma Corydalis on focal cerebral infarct in ischemia-reperfusion injured rats.
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OBJECTIVE
To investigate the effect of Rhizoma Corydalis (RC) on focal cerebral infarct.
METHODS
A total of 30 Sprague-Dawley (SD) rats were studied. Focal cerebral infarct was established b y occluding the bilateral common carotid arteries and the right middle cerebral artery for 90 min. After 24 h
[Effects of Corydalis ambailis migo total alkaloids on experimental cerebral ischemia].
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OBJECTIVE
To observe the protective effects of Corydalis ambailis migo total alkaloids (COAMTA) on cerebral ischemia/reperfusion injury in rats and to investigate its mechanism.
METHODS
The effects of COAMTA on decapitated gasping mouse model and rat model of middle cerebral artery ischemia (2
[Analysis of chemical constituents of anti-myocardial ischemia fraction of Corydalis yanhusuo].
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OBJECTIVE
To establish the HPLC fingerprint of anti-myocardial ischemia fraction of Corydalis yanhusuo, and to investigate its chemical constituents by LC-MS-MS.
METHODS
The separation was performed at 30 degrees C on a Dikma Diamonsil C18 column (4.6 mm x 250 mm, 5 microm) by isocratic elution with
l-Tetrahydropalmatine, an active component of Corydalis yanhusuo W.T. Wang, protects against myocardial ischaemia-reperfusion injury in rats.
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l-Tetrahydropalmatine (l-THP) is an active ingredients of Corydalis yanhusuo W.T. Wang, which protects against acute global cerebral ischaemia-reperfusion injury. In this study, we show that l-THP is cardioprotective in myocardial ischaemia-reperfusion injury and examined the mechanism. Rats were
Chinese Medicine She-Xiang-Xin-Tong-Ning, Containing Moschus, Corydalis and Ginseng, Protects from Myocardial Ischemia Injury via Angiogenesis.
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The Chinese patent medicine She-Xiang-Xin-Tong-Ning (SXXTN) is a clinical medication for coronary heart disease (CHD) and angina pectoris. This study aimed to investigate pharmacological effects of SXXTN and elucidate the role in angiogenesis on human umbilical vein endothelial cells (HUVECs)
[Effects of four components of Rhizoma Corydalis on anoxia and peroxidation injuries in neonatal cardiomyocytes].
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OBJECTIVE
To observe the effects of tetrahydropalmatine, dehydrocorydaline, berberine and palmatine on anoxia and peroxidation injuries in cardiomyocytes, and study the marterial basis of the anti-ischemia effect on myocardium of Rhizoma Corydalis.
METHODS
Neonatal rat cardiomyocytes were cultured
Fingerprint-efficacy study of the quaternary alkaloids in Corydalis yanhusuo.
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BACKGROUND
Corydalis yanhusuo is a well-known Chinese herbal medicine that is commonly applied as an analgesic agent in clinic using for thousands of years. Resent research showed that the quaternary ammonium alkaloids from Corydalis yanhusuo have a significant effect on myocardial ischemia.
Advances in phytochemical and modern pharmacological research of Rhizoma Corydalis.
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ABSRACTContext:Rhizoma Corydalis (RC) is the dried tubers of Corydalis yanhusuo (Y. H. Chou and Chun C. Hsu) W. T. Wang ex Z. Y. Su and C. Y. Wu (Papaveraceae). Traditionally, RC is used to alleviate pain such as headache, abdominal pain, and epigastric pain. Modern medicine
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