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cryptococcosis/albumin
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Characterization of a suppressor factor that regulates phagocytosis by macrophages in murine cryptococcosis.
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A T-suppressor factor which inhibits the phagocytic activity of a macrophage subset has been further characterized. This suppressor factor was first described for a murine model of cryptococcosis but was later found to be common to models of immunologic unresponsiveness. The suppressor factor was
Immunosuppression in experimental cryptococcosis in rats: modification of macrophage functions by T suppressor cells. Macrophages functions in cryptococcosis.
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The influence of lymphocytes on the modulation of macrophage functions in altered immune states induced by Cryptococcus neoformans infection in rats has been investigated. In this report we observed a decrease of 'in vitro' phagocytic activity by peritoneal cells (PC) from rats that received T
Immunosuppression in experimental cryptococcosis in rats. Induction of efferent T suppressor cells to a non-related antigen.
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Using a rat model, we have previously demonstrated that infection with Cryptococcus neoformans can trigger the production of a series of suppressor cells that specifically inhibit the cell-mediated immune response to a non-related antigen, human serum albumin (HSA), that has been injected 7 days
Immunosuppression in experimental cryptococcosis: variation of splenic and thymic populations and expression of class II major histocompatibility complex gene products.
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Previous studies from our laboratory have shown that infection with Cryptococcus neoformans can trigger the production of a series of suppressor cells that specifically inhibit the cell-mediated immune response to a nonrelated antigen, the human serum albumin (HSA). In the present study, we
Immunosuppression in experimental cryptococcosis in rats. Induction of afferent T suppressor cells to a non-related antigen.
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To demonstrate the nature of the suppressor cells elicited in rats infected with Cryptococcus neoformans and immunized with human serum albumin (HSA), spleen mononuclear (SpM) cells were fractionated through a nylon wool column. The adherent and non-adherent populations were collected and
[Update on neuromeningeal cryptococcosis in Dakar].
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This study was carried out to provide current information on neuromeningeal cryptococcosis at the Infectious Diseases Clinic in Fann Teaching Hospital in Dakar. Epidemiological, clinical, biological and therapeutic data were collected retrospectively from files of patients treated between 1999 and
Pulmonary cryptococcosis presenting with a large cavity.
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A 78-year-old woman who was receiving corticosteroids for rheumatoid arthritis was admitted to our hospital to have her fever, hemoptysis, diarrhea, and chest x-ray abnormalities, which were unresponsive to antibiotics, investigated. A chest computed tomography scan revealed infiltrative shadows and
[Partial purification and properties of protease from Torula thermophila].
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11-Fold purified protease preparation is isolated from cultural medium of Torula thermophila UzPT-1 by means of ammonium sulphate precipitation and gel chromatography through Sephadex G-100. Disc polyacrylamide gel electrophoresis revealed two portease components, one of them possessing proteolytic
Disseminated cryptococcosis with hepatic dysfuction as the initial manifestation in an immunocompetent adult.
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Disseminated cryptococcosis is rare in immunocompetent hosts and hepatic manifestations as the presenting feature is further rare. We report a case of disseminated cryptococcosis with hepatic involvement as an initial manifestation in a previously healthy, immunocompetent adult. A young married
Effect of torula yeast on growth performance, diarrhea incidence, and blood characteristics in weanling pigs
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Two experiments were conducted to test the hypothesis that torula yeast may replace animal and plant proteins in diets for weanling pigs without negatively impacting growth performance or blood characteristics. In Exp. 1, 128 weanling pigs (6.71 ± 0.76 kg) were allotted to 4 treatments with 4 pigs
Clinical impact of advanced chronic kidney disease in patients with non-HIV pulmonary cryptococcosis.
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Immunosuppression in experimental cryptococcosis in rats. Induction of thymic suppressor cells.
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The presence of the microorganism, cortical hyperplasia and germinal centers was detected in the thymus of rats infected with 10(7) viable Cryptococcus neoformans cells and immunized at 7 days afterwards with 2.5 mg (0.1 ml) of human serum albumin (HSA) incorporated to complete Freund's adjuvant
Evaluation of Cryptococcus neoformans galactoxylomannan-protein conjugate as vaccine candidate against murine cryptococcosis.
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Galactoxylomannan (GalXM) is a complex polysaccharide produced by the human pathogenic fungus Cryptococcus neoformans that mediates profound immunological derangements in murine models. GalXM is essentially non-immunogenic and produces immune paralysis in mice. Previous studies have attempted to
Non-specific immunosuppression in experimental cryptococcosis in rats.
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The delayed type hypersensitivity response to human serum albumin (HSA) of rats infected intraperitoneally with 10(7) viable C. neoformans cells, and 7 days after, immunized with human serum albumin was significantly diminished (p less than 0.05) when compared with the response observed in rats
Super aggregated form of Amphotericin B: a novel way to increase its therapeutic index.
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Amphotericin B (AmB)-deoxycholate micellar formulation, Fungizone®, is the drug of choice for the treatment of unidentified mycotic infections. However, it usage has been marred by long therapeutic regimes and severe side effects. The less toxic lipid associated AmB formulations have been limited by
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