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Effects of hypoxia at different life stages on locomotory muscle phenotype in deer mice native to high altitudes.
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Animals native to high altitude must overcome the constraining effects of hypoxia on tissue O2 supply to support routine metabolism, thermoregulation in the cold, and exercise. Deer mice (Peromyscus maniculatus) native to high altitude have evolved an enhanced aerobic capacity in hypoxia, along with
Prenatal development of coronary arteries in the rat: morphometric patterns.
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The aim of this work was to address morphometric patterns of coronary artery (c.a.) development in the rat based on serial section analysis of hearts at different stages of prenatal development. Studies were performed on foetal hearts 15-21 days (ED) post-conception. Paraffin sections were stained
Insulin-like growth factor-1 mRNA is increased in deafferented hippocampus: spatiotemporal correspondence of a trophic event with axon sprouting.
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Deafferentation is known to induce axonal sprouting in adult brain, but the signals that direct this response are not understood. To evaluate the possible roles of insulin-like growth factor-1 (IGF-1) and basic fibroblast growth factor (bFGF) in central axonal sprouting, the present study used in
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