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Halaman 1 dari 18 hasil
7,7-Dimethylaporphine and Other Alkaloids from the Bark of Guatteria friesiana.
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Phytochemical investigation of the bark of Guatteria friesiana afforded 12 new aporphines (1-12), along with nine known alkaloids (13-21). The structures of the new alkaloids were determined on the basis of spectroscopic data interpretation. The cytotoxic activity of the isolated compounds against a
In vitro screening for antiplasmodial activity of isoquinoline alkaloids from Brazilian plant species.
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In the search for new antimalarial agents, nine Brazilian plant species were selected, from the Annonaceae (6), Menispermaceae (2) and Siparunaceae (1) families naturally occurring at the cerrado and Atlantic rainforest regions, in order to investigate their in vitro antiplasmodial activity. The
Alkaloids from the bark of Guatteria hispida and their evaluation as antioxidant and antimicrobial agents.
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Phytochemical investigation of the bark of Guatteria hispida afforded three new alkaloids, 9-methoxy-O-methylmoschatoline (1), 9-methoxyisomoschatoline (2), and isocerasonine (3), along with 10 known alkaloids, 8-oxopseudopalmatine (4), O-methylmoschatoline (5), lysicamine (6), liriodenine (7),
New aporphine alkaloids from guatteria foliosa.
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Four new alkaloids were obtained from Guatteria foliosa, namely, the noraporphines (-)-3-methoxyputerine [1] and (+)-norguattevaline [2], the more highly oxidized (+)-3-methoxyguattescidine [3], and the oxoaporphine 3-methoxyoxoputerine [4]. Among several other known alkaloids also found in this
[Alkaloids from Annonaceae XLVII*: Alkaloides of Guatteria ouregou**].
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The Guianese Annonaceous plant GUATTERIA OUREGOU D UN. has yielded fourteen isoquinoline alkaloids, five of which are novel. They belong to several structural types; attention is specially drawn to three original skeletons, namely 7-hydoxy-7-methyl aporphinoids, 7- GEM-dimethyl aporphinoids and
Minor alkaloids from Guatteria dumetorum with antileishmanial activity.
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Nine known alkaloids [(+)-isodomesticine (1), (+)-norisodomesticine (2), (+)-nantenine ( 3), (+)-neolitsine (4), (+)-lirioferine (5), (+)-N-methyllaurotetanine (6), (+)-norlirioferine (7), (+)-isoboldine (8) and (+)-reticuline (9)] were isolated from young leaves of Guatteria dumetorum. Their
Guaianolide sesquiterpene lactones and aporphine alkaloids from the stem bark of Guatteria friesiana.
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Three guaianolide sesquiterpenes, denoted guatterfriesols A-C, and four aporphine alkaloid derivatives were isolated from the stem bark of the Amazonian plant Guatteria friesiana. Thus far, sesquiterpene lactones have not been described in Annonaceae. Structures of the previously undescribed
Structure elucidation of norlaureline and puterine, new noraporphine alkaloids from Guatteria elata.
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The structures of norlaureline (1) and puterine (4), new noraporphine alkaloids isolated from Guatteria elata (Annonaceae), were established by interpretation of the optical rotation, uv, ir, pmr, and mass spectral data of their N-acetyl derivatives. Proposed structures were confirmed by
Bisbenzylisoquinoline alkaloids from Guatteria boliviana (Annonaceae).
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Together with known alkaloids, five new bisbenzylisoquinoline derivatives were isolated from the stem bark of Guatteria boliviana (Annonaceae), puertogalines-A 1 and -B 2, (+)-guatteboline 3, philogaline 4 and (-)-antioquine 5. Their structures were elucidated by spectrometric methods and their
Aporphine alkaloids from Guatteria spp. with leishmanicidal activity.
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Fractionation of Guatteria amplifolia yielded the alkaloids xylopine (1), nornuciferine (4), lysicamine (6), and laudanosine (5). Fractionation of Guatteria dumetorum yielded the alkaloids cryptodorine (2) and nornantenine (3). Compounds 1-4 demonstrated significant activity against Leishmania
Antimicrobial photodynamic effect of extracts and oxoaporphine alkaloid isomoschatoline from Guatteria blepharophylla.
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Photodynamic Therapy, a tumor therapy idealized at the beginning of the last century, emerges nowadays as a promising treatment alternative against infectious diseases. In this study we report a bioguided study of Guatteria blepharophylla phytoderivatives for antimicrobial PDT. Crude extracts and
Leishmanicidal activity of the alkaloid-rich fraction from Guatteria latifolia.
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Leishmaniasis is caused by protozoan parasites belonging to the genus Leishmania and includes cutaneous, mucocutaneous and visceral clinical forms. The drugs currently available for leishmaniasis treatment are pentavalent antimonials, amphotericin B and miltefosine, which present high toxicity,
[Guattegaumerine, New Bisbenzylisoquinoline Alkaloid from Guatteria gaumeri.].
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The aqueous-alcoholic extract of the bark of GUATTERIA GAUMERI (Mexican Annonaceae) is used for the treatment of cholelithiasis and hypercholesterolemia. Therefore it seems very interesting to perform a phytochemical study of this drug in order to know its composition and to determine, if possible,
Aporphinoid Alkaloids from Guatteria schomburgkiana Leaves (1).
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Alkaloids of Guatteria diospyroides.
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