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Halaman 1 dari 52 hasil
Transdermal hyoscine and postoperative nausea and vomiting.
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Forty-two patients, undergoing major gynaecological surgery, were randomly allocated to have a patch applied to the skin behind one ear, containing either hyoscine or placebo. They were followed up at 24-hour intervals for 3 days postoperatively and divided into matched pairs for statistical
Double blind comparison of transdermal hyoscine and placebo for the prevention of postoperative nausea.
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Transdermal hyoscine (Scopoderm, Ciba-Geigy) has been compared with placebo in 283 female patients. The hyoscine patch had no significant effect on postoperative nausea or vomiting. In contrast with earlier studies, there was no correlation between previous experiences of nausea (motion, pregnancy
Prevention of nausea and vomiting with transdermal hyoscine in adults after middle ear surgery during general anaesthesia.
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In a double-blind, randomized study, we have compared the efficacy of transdermal hyoscine in the prevention of nausea and vomiting with placebo in 60 young, ASA I-II patients after middle ear surgery during general anaesthesia. In the placebo group, 27% and 43% of patients suffered from nausea and
Effect of transdermal hyoscine on nausea and vomiting during and after middle ear surgery under local anaesthesia.
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The efficacy of transdermal hyoscine in the reduction of nausea, retching and vomiting was compared with placebo during and after stapedo- and tympanoplasty under local anaesthesia in a double-blind, prospective and randomized study. In the placebo group (n = 29), 69% of the patients were free from
Prevention of postoperative nausea and vomiting with transdermal hyoscine in children using patient-controlled analgesia.
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We have studied 40 children aged 6-14 yr undergoing abdominal surgery under general anaesthesia with extradural block; they were allocated randomly to receive transdermal hyoscine (loading dose 140 micrograms, followed by 5 micrograms h-1) or placebo for the duration of postoperative analgesia with
Preoperative transdermal hyoscine for the prevention of postoperative nausea and vomiting.
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In a randomised, double-blind study, a transdermal patch containing either hyoscine or placebo was applied post-auricularly in 190 adult patients under 65 year old, seven to twelve hours prior to their undergoing minor orthopaedic or plastic surgery under thiopentone/nitrous oxide/halothane general
Effect of transdermal hyoscine on nausea and vomiting after surgical correction of prominent ears under general anaesthesia.
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In a double-blind, randomized study, we have compared the efficacy of transdermal hyoscine with placebo in the reduction of nausea and vomiting in 50 patients, ASA I-II, after surgical correction of prominent ears under general anaesthesia. In the placebo group, 28%, 4% and 48% of patients suffered
Prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy. A prospective randomized study of metoclopramide and transdermal hyoscine.
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OBJECTIVE
To compare the antiemetic effects of metoclopramide and hyoscine in patients after laparoscopic cholecystectomy.
METHODS
Prospective, randomised trial.
METHODS
University hospital, Sweden.
METHODS
100 consecutive patients median age 49 years (range 21-79) of whom 9 were withdrawn after
Comparison of the neurokinin-1 antagonist GR205171, alone and in combination with the 5-HT3 antagonist ondansetron, hyoscine and placebo in the prevention of motion-induced nausea in man.
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OBJECTIVE
In man a neurokinin-1 (NK1) receptor antagonist has previously been shown to be ineffective in the prevention of motion-induced nausea. The antiemetic efficacy of NK1 receptor antagonists against chemotherapy-induced emesis is, however, enhanced when combined with a 5-HT3 receptor
Transdermal hyoscine and postoperative nausea and vomiting.
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Transdermal hyoscine and postoperative nausea and vomiting.
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Effect of transdermal hyoscine on nausea and vomiting.
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[The effect of hyoscine-n-butylbromide on postanesthetic nausea and ether narcosis].
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Comparison of the effects of a selective muscarinic receptor antagonist and hyoscine (scopolamine) on motion sickness, skin conductance and heart rate.
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OBJECTIVE
Hyoscine (scopolamine), which is effective in the prophylaxis of motion sickness, shows similar binding affinities to all of the five known muscarinic receptor sub-types. The effectiveness of hyoscine was compared with zamifenacin (UK-76654), which binds selectively to the muscarinic M3
Oesophageal spasm, vomiting and hyoscine hydrobromide patch.
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We report the case of a 60-year-old woman with metastatic breast cancer whose intractable nausea and vomiting were effectively managed with a hyoscine hydrobromide (scopolamine) patch. Contrast swallow revealed oesophageal spasm to be the underlying cause. Symptom relief may be attributed to the
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