14 hasil
BACKGROUND OF THE INVENTION
In general, the invention is related to methods for treating, ameliorating, or attenuating an ischemia-reperfusion injury.
Ischemia-reperfusion (I/R) injury represents a leading cause of morbidity and mortality and is a major clinical problem. Reperfusion of tissues and
BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
BACKGROUND OF THE INVENTION
The present invention relates to active polymorphs of 4-[2-(5-cyano-thiazol-2-ylamino)-pyridin-4-ylmethyl]-piperazine-1-carboxyl ic acid methylamide, which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these polymorphs,
BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
FIELD OF THE INVENTION
This invention relates to substituted compounds of formula (I): ##STR2##
wherein Ar.sub.1, X, Y, P, Q and Het are defined below, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases resulting from inappropriate cell
FIELD OF THE INVENTION
This invention relates to substituted compounds of formula (I): ##STR2##
wherein Ar.sub.1, X, Y, P, Q and Het are defined below, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases resulting from inappropriate cell
TECHNICAL FIELD OF THE INVENTION
The present invention relates to methods for the prophylactic and therapeutic treatment of retinal ischemia and ocular inflammation.
BACKGROUND OF THE INVENTION
Retinal ischemia occurs as a result of occlusion of a retinal blood vessel, such as occlusion of the
TECHNICAL FIELD OF THE INVENTION
This invention relates to substituted compounds of formula (I): ##STR2##
wherein Ar.sub.1, R.sub.a, R.sub.4, R.sub.5, X and Y are defined below, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases resulting
TECHNICAL FIELD OF THE INVENTION
This invention relates to substituted compounds of formula (I): ##STR2##
wherein Ar.sub.1, R.sub.a, R.sub.4, R.sub.5, X and Y are defined below, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases resulting
FIELD OF THE DISCLOSURE
The present disclosure relates to the field of medical diagnostics.
BACKGROUND
An aim of modern medicine is to provide personalized or individualized treatment regimens. Those are treatment regimens which take into account a patient's individual needs or risks. A particularly
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to compounds that act to block calcium channels; methods of using the compounds to treat stroke, cerebral ischemia, pain, head trauma, or epilepsy; and to pharmaceutical compositions that contain the compounds of the
CROSS REFERENCE
This application is a 371 of PCT/US99/12276 filed Jun. 2, 1999.
BACKGROUND OF THE INVENTION
FIELD OF THE INVENTION
The present invention relates to compounds that act to block calcium channels; methods of using the compounds to treat stroke, cerebral ischemia, pain, head trauma, or
BACKGROUND
The present invention is directed to glycosulfopeptides and methods of their use in treating inflammation and disorders related to leukocyte rolling mediated by P-selectin binding.
Inflammation is the reaction of vascularized tissue to local injury. This injury can have a variety of
TECHNICAL FIELD
The present invention relates to a new revascularization cell population derived from a mononuclear cell population and a method of inducing differentiation thereof. More specifically, the present invention relates to a new revascularization cell population that is derived from