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limonin glucoside/kanker
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Citrus limonoids and curcumin additively inhibit human colon cancer cells.
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In the current study, we examined the ability of limonoids, including limonin, limonin glucoside (LG) and curcumin, to inhibit proliferation of human colon cancer (SW480) cells. Additionally, we studied the effect of combining these two classes of natural compounds on inhibition of proliferation and
Limonoids and their anti-proliferative and anti-aromatase properties in human breast cancer cells.
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Lemons are a widely used citrus crop and have shown several potential health benefits. In the present study, the mechanism and effectiveness of the anti-cancer and anti-aromatase properties of limonoids were investigated for the first time. Defatted lemon (Citrus lemon L. Burm) seed powder was
Simultaneous separation and identification of limonoids from citrus using liquid chromatography-collision-induced dissociation mass spectra.
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Limonoids are considered as potential cancer chemopreventive agents and are widely distributed in the Citrus genus as aglycones and glucosides. In the present study, reversed-phase HPLC coupled with CID mass spectra was developed for the simultaneous separation and identification of aglycones and
Citrus limonin and its glucoside inhibit colon adenocarcinoma cell proliferation through apoptosis.
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The current study was an attempt to elucidate the mechanism of human colon cancer cell proliferation inhibition by limonin and limonin glucoside (LG) isolated from seeds of Citrus reticulata. The structures of purified compounds were confirmed by NMR and quantified using HPLC. These compounds of
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