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lygodium polycarpum/glutathione
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Protective effect of Lygodium flexuosum (L.) Sw. (Lygodiaceae) against D-galactosamine induced liver injury in rats.
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The protective effect of Lygodium flexuosum n-hexane extract against D-galactosamine was evaluated in Wistar rats. In preventive groups extract was administered at 48, 24 and 2h before D-galactosamine intoxication whereas in post-treatment groups extract were administered 2, 24 and 48 h after
Protective effect of Lygodium flexuosum (L.) Sw. extract against carbon tetrachloride-induced acute liver injury in rats.
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The hepatoprotective potential of Lygodium flexuosum (L.) Sw. was evaluated in male Wistar rats against carbon tetrachloride-induced liver damage in preventive and curative models. Toxic control and n-hexane extract-treated rats received a single dose of CCl4 (150 microL/100g, 1:1 in corn oil).
Lygodium flexuosum extract down regulates the expression of proinflammatory cytokines in CCl4-induced hepatotoxicity.
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OBJECTIVE
To examine the downregulation of proinflammatory cytokines in a time-dependent manner on carbon tetrachloride induced toxicity in experimental animals.
METHODS
CCl(4) (150 μL/100 g) was dissolved in corn oil (1:1 v/v %) and administered orally. Group I was treated as normal control and
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