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Marrubiin, a constituent of Leonotis leonurus, alleviates diabetic symptoms.
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OBJECTIVE
Marrubiin and an organic extract of Leonotis leonurus were tested in vitro and in vivo for their antidiabetic and anti-inflammatory activities.
METHODS
INS-1 cells were cultured under normo- and hyperglycemic conditions conditions. An in vivo animal model confirmed the biological
The cardioprotective effects of marrubiin, a diterpenoid found in Leonotis leonurus extracts.
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BACKGROUND
Leonotis leonurus L. (Lamiaceae) is used as a traditional medicine for a variety of ailments in South Africa. The diterpene marrubiin is the major product constituent in specimens of this plant occurring in South Africa.
METHODS
Marrubiin isolated from South African specimens of L.
Protective effects of marrubiin improve endometriosis through suppression of the expression of RANTES.
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Marrubiin can improve blood and lymph microcirculation disturbance, and has pharmacological effects in myocardial protection, anti‑inflammation and anti‑oxidation. The aim of the present study was to evaluate the protective effects of marrubiin on endometriosis through suppression of the expression
Antioedematogenic effect of marrubiin obtained from Marrubium vulgare.
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This paper describes the antioedematogenic profile of marrubiin (1), the main constituent of Marrubium vulgare, a medicinal plant used in folk medicine of several countries to treat different pathologies. Compound (1) was analyzed in a model of microvascular leakage in mice ears. The results show
Marrubium vulgare L.: A Phytochemical and Pharmacological Overview
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Marrubium vulgare is a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies, M. vulgare acts as a good antioxidant agent, and due to this,
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