maysin/amiloidosis

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Maysin and Its Flavonoid Derivative from Centipedegrass Attenuates Amyloid Plaques by Inducting Humoral Immune Response with Th2 Skewed Cytokine Response in the Tg (APPswe, PS1dE9) Alzheimer's Mouse Model.

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Alzheimer's disease (AD) is a slow, progressive neurodegenerative disease and the most common type of dementia in the elderly. The etiology of AD and its underlying mechanism are still not clear. In a previous study, we found that an ethyl acetate extract of Centipedegrass (CG) (i.e., EA-CG)

Maysin plays a protective role against α-Synuclein oligomers cytotoxicity by triggering autophagy activation

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Parkinson's disease (PD) is a widespread neurodegenerative disorder characterized by the progressive loss of neurons. The accumulation of aggregated forms of the α-Synuclein (Syn) protein is the main cause of neurotoxicity in PD by disrupting cellular homeostasis until neuronal death. Scientific

Distribution of Four Bioactive Flavonoids in Maize Tissues of Five Varieties and Correlation with Expression of the Biosynthetic Genes.

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Flavonoids are characteristic in maize and have diverse biological functions. C-Glycosylflavones are neuroprotective against β-amyloid-induced tau hyperphosphorylation and neurotoxicity in SH-SY5Y cells, which is relevant to Alzheimer's disease prevention and treatment. The content of the flavonoids

Protective effect of centipedegrass against Aβ oligomerization and Aβ-mediated cell death in PC12 cells.

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BACKGROUND Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the abnormal accumulation of β-amyloid (Aβ). Multiple Aβ-aggregated species have been identified, and neurotoxicity appears to be correlated with the amount of non-fibrillar oligomers. Potent inhibitors of Aβ

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