Arthritis

Determine of percentage of each type of arthritis in children, it's prognosis and outcome of treatment in comparison with international guidelines

Observation

Arthritis in Assiut University Children Hospital

Using full history, a clinical examination and investigations can diagnose different types of arthritis attending assiut university children hospital and define prevalence of different types of arthritis

Mohamed Masoud Adb-Elmonem

Principal Investigator of pediatrics

Assiut University

Osteoporosis

Intravenous zoledronic acid 0.025mg/kg at baseline, 6 months, 12 months and 18 months

Zoledronic Acid

Subcutaneous denosumab 1.0mg/kg at baseline, 6 months, 12 months and 18 months

Denosumab

Children's Hospital of Eastern Ontario

Denosumab for the Treatment of Osteoporosis in Children: A Pilot Study

A Single-Blinded, Randomized, Controlled, Phase 2 Pilot Study to Evaluate the Safety and Efficacy of Denosumab Compared to Zoledronic Acid for the Treatment of Osteoporosis in Children

To observe the changes in serum ionized calcium levels at 48 hours following the administration of denosumab versus zoledronic acid. Hypocalcemia at 48 hours has been chosen as the primary outcome since this is a clinically important side effect of both denosumab and zoledronic acid, and 48 hours is around the time of the anticipated calcium nadir

Dr. Leanne Ward

Rheumatoid Arthritis, Ankylosing Spondylitis, Systemic Lupus Erythematosus/Antiphospholipid Syndrome, FMF, Cryopyrin-Associated Periodic Syndromes (CAPS)/TNF-receptor Associated Periodic Syndrome (TRAPS), Vasculitis, Uveitis, Myositis, Crohn's Disease, Ulcerative colitis, Type 1 Diabetes

knee arthritis, hip arthritis, muscular dystrophy, healthy subject

Healthy Volunteer

Rheumatoid Arthritis

Ankylosing Spondylitis

Systemic Lupus Erythematosus/Antiphospholipid Syndrome

Cryopyrin-Associated Periodic Syndromes /TNF-receptor Associated Periodic Syndrome

Vasculitis

Uveitis

Myositis

Crohn's Disease

Ulcerative Rectocolitis

Type 1 Diabetes

Unclassified IAD Knee and/or Hip Arthritis, Muscular Dystrophy

1: AID groups

2: Control groups

Rhumatologie - Hôpital Saint-Antoine

CIC Paris-Est, Hôpital PITIE SALPETRIERE

Phenomics in Autoimmune and Inflammatory Diseases

Clinical and Multi-omics Cross-phenotyping of Patients With Autoimmune and Auto-inflammatory Diseases

Identification of novel molecular and cellular pathways involved either in specific diseases or across the IAD continuum through a multiparametric approach

Identification of new biomarkers and potential therapeutic by multiscale analysis

muscular dystrophies/demam

Arthritis in Assiut University Children Hospital

Denosumab for the Treatment of Osteoporosis in Children: A Pilot Study

Phenomics in Autoimmune and Inflammatory Diseases

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