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[Invasive mycoses during hematopoietic stem cell transplantation].
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OBJECTIVE
To define the frequency, etiology, and risk factors of invasive mycoses (IM) in patients with allogeneic (allo) and autologous (auto) hematopoietic stem cell transplantation (HSCT) and to evaluate the impact of IM on overall survival (OS).
METHODS
Data on 356 patients after allo-HSCT (n =
Disseminated mycoses in cattle. A study on nine autopsy cases.
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Nine cases affected with disseminated mucormycosis (1.3% of all autopsy cases and 20.0% of systemic mycosis) were found among bovine systemic mycosis examined from 1975 to 1985. The disseminated lesions were found in the lungs (3 cattle), heart (2 cattle), liver (2 cattle), spleen (1 beef cattle),
[Manifestations of systemic mycoses and related infections in the central nervous system].
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In daily practice mycotic infections of the CNS have become more and more frequent. The main causes are the wide-ranging use of corticosteroids, immunosuppressive, cytostatic drugs and antibiotics, the spreading of AIDS, the increasing number of surviving immature newborns. To illustrate the
Host-parasite relationship in opportunistic mycoses.
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Aspergillosis and mucormycosis are opportunistic fungal infections that share several unique features. The etiologic agents of aspergillosis and mucormycosis are ubiquitous in the environment, but are opportunistic organisms and usually infect only patients predisposed by some underlying disease or
[Mucoraceae mycoses: clinical aspects and pathology in ten patients].
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Zygomycosis is characterized by a very high lethality, often favoured by rapid fungal growth in blood vessels causing the formation of thrombi and infarcts in several organs, a disease poor in symptoms. A disseminated mycosis normally is a complication of a granulocytopenia which is in our days more
The role of CT in the evaluation of patients with intracranial CNS infectious-inflammatory disorders.
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Infections of the CNS may be caused by diverse etiologies. These include bacteria, viruses, mycoses, protozoa, helminths. In these CNS infections there is a breakdown in the blood-brain barrier. The most common clinical forms of intracranial CNS infections include meningitis, cerebritis-abscess
[Zygomycoses: clinical aspects and pathology in 10 patients].
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Deep fungal infections caused by zygomycetes (so-called mucormycoses) are rare. Whereas in the past rhinocerebral mycosis dominated, today a wide range of clinical manifestations must be expected, especially pulmonary infections and invasion of vessel walls with systemic infarction. On the basis of
The emergence of candidosis. The dominant postmortem cerebral mycosis.
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Comparable human postmortem surveys in central Kentucky and southern Florida have demonstrated an altered pattern of cerebral mycoses due primarily to therapeutic manipulations. From both states 8,975 complete autopsies yielded 39 patients with histologically verified cerebral mycoses. The most
[Hospital infection of bronchopulmonary aspergillosis in infants and small children].
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Routine histological investigations of the lungs of 38 children led to the discovery during the second half of 1970 of 4 cases of pulmonary aspergillosis in hospitalized children between 3 1/2 weeks and 2 years of age. Those cases represented 10.5% of all children, autopsiated during this period
[A pathological study on cerebral mycosis].
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The histopathological examination was performed in search of cerebral mycosis in autopsy cases at our department during the 6 years from 1976 to 1981. The cerebral mycoses were histopathologically verified in seven cases, although brain tissue was examined in only 46% of 528 autopsy cases. All cases
Central nervous system coccidioidomycosis: a clinicopathologic study of treatment with and without amphotericin B.
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The clinical and pathologic findings in 32 patients with central nervous system (CNS) coccidioidomycosis were studied. Seventeen patients had received more than 1.5 g of amphotericin B (AMB), chiefly intravenously, during treatment periods of up to eight years. Eight patients had received 246 mg to
[The initial CT findings in patients suffering from invasive pulmonary aspergillosis].
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OBJECTIVE
To approach the initial CT findings of invasive pulmonary aspergillosis (IPA) in patients with immunosuppression.
METHODS
All consecutive adult patients who met the diagnostic criteria of the 2008 European Organization for Research and Treatment of Cancer/ Mycoses Study Group (EORTC/MSG)
[Pulmonary zygomycosis--a rare angioinvasive fungal infection].
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Zygomycosis caused by Rhizopus species is an aggressive and rapidly progressive opportunistic fungal infection in immunocompromised patients. It comprises mucocutaneous, rhinocerebral, pulmonary, urological and disseminated infections. Predisposing factors are immunosuppression owing to severe
[Nosocomial fungal infections, analysis of 149 cases].
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OBJECTIVE
To investigate the manifestation, diagnosis, antifungal therapy and outcome of nosocomial fungal infections.
METHODS
The clinical data of 149 patients with nosocomial fungal infections admitted in the PUMC hospital from Dec. 1981 to Nov. 2001, 67 males and 82 females with an average age of
[Dementia in Patients with Central Nervous System Mycosis].
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Central nervous system (CNS) mycosis is a potentially life-threatening but treatable neurological emergency. CNS mycoses progress slowly and are sometimes difficult to distinguish from dementia. Though most patients with CNS mycosis have an underlying disease, such as human immunodeficiency virus
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