nageia laeta/radang

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Anti inflammatory activity of Myrica nagi Linn. Bark.

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The present study evaluated the anti inflammatory activity of ethyl acetate and aqueous extracts of bark of M. nagi using carrageenan and histamine induced rat paw edema. Adult Wistar albino rats were subjected to carrageenan and histamine induced rat paw edema tests. In carrageenan induced rat paw

Incorporation of sciadonic acid into cellular phospholipids reduces pro-inflammatory mediators in murine macrophages through NF-κB and MAPK signaling pathways.

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Sciadonic acid (SCA; Δ5,11,14-20:3), a non-methylene-interrupted polyunsaturated fatty acid (NMIFA), can substitute for arachidonic acid (AA) and reduce prostaglandin E2 (PGE2) synthesis in macrophages. However, little is known about how SCA exerts its anti-inflammatory effects. The objectives of

New podolactones from the seeds of Podocarpus nagi and their anti-inflammatory effect.

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Podolactones are a class of structural diverse diterpenoid lactones, mainly isolated from the Podocarpus species. Several bioactivities have been disclosed for podolactones, including cytotoxicity and anti-atherosclerosis. In this study, the seeds of P. nagi were isolated by comprehensive

Epidermal anti-Inflammatory properties of 5,11,14 20:3: effects on mouse ear edema, PGE2 levels in cultured keratinocytes, and PPAR activation.

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BACKGROUND 5,11,14 20:3 is similar to 20:4n-6 but lacks the internal Delta8 double bond essential for prostaglandin and eicosanoid synthesis. When previously fed to laboratory animals as a gymnosperm seed oil component it has shown anti-inflammatory properties. RESULTS Herein, topically applied

Molecular Mechanisms of Action of Myricetin in Cancer.

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Natural compounds such as paclitaxel and camptothecin have great effects on tumor treating. Such natural chemicals often achieve anti-tumor effects through a variety of mechanisms. Therefore, it is of great significance to push forward the studies on the anticancer mechanism of natural anticancer to

Cross-linked fibrin degradation products (D-dimer), plasma cytokines, and cognitive decline in community-dwelling elderly persons.

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OBJECTIVE To investigate the effect of coagulation and inflammatory pathway activation on future cognitive decline in older persons. METHODS Prospective cohort study. METHODS Rural and urban communities in North Carolina. METHODS Community-dwelling older people enrolled in the Duke Established

Relations of a marker of endothelial activation (s-VCAM) to function and mortality in community-dwelling older adults.

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BACKGROUND We wished to determine if a marker of endothelial dysfunction/activation soluble vascular cell adhesion molecule (s-VCAM)-was related to functional status and mortality in community-dwelling older adults independent of the known effects of markers of inflammation and

Cytokine induction by LVAD in the canine kidney.

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BACKGROUND The outcome of left ventricular assist device (LVAD) support is reported to be associated with proinflammatory cytokines. We investigated the effect of LVAD support on renal function and the resultant cytokine induction. METHODS A prospective experimental study was performed using 15

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