Group1 is control group and participants do not need intervention.

Group 2 is vinegar Group and participants in this group are asked to drink 15ml vinegar(Ninghuafu, Sanxi, China)after dinner at noon and evening respectively for a period of four weeks.

Urolithiasis

Each participant in vinegar group drink 15ml vinegar(Ninghuafu,Sanxi,China)after dinner at noon and evening respectively for a period of four weeks.

Vinegar group

Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University

Effect of Vinegar Consumption on 24-hour Urinary Risk Factors Associated With Stone Formation

The Effect of Vinegar Consumption on 24-hour Urinary Risk Factors Associated With Calcium Oxalate Urinary Stone Formation: a Randomised Controlled Trial

To compare the change of 24-hour urinary risk factors associated with calcium oxalate urinary stone formation which include Ph, volume, creatinine, oxalate, citrate, phosphate, uric acid, calcium, magnesium, sodium and chloride of 24-hour urine between two groups on the 7th,14th,21th and 28th day after drinking vinegar.

To compare the change of blood biochemical parameters which include fasting serum glucose, creatinine, urea, uric acid, high-density lipoprotein, low-density lipoprotein, triglycerides,serum total bile acid, cholesterol, sodium, potassium, calcium and chloride ions before grouping and on the 28th day after drinking vinegar.

To compare the change of blood oxidative stress markers which include blood protein product(AOPP),MDA,glutathion peroxidase(GSH-PX),superoxide dismutase(SOD) and catalase activity(CAT) before grouping and on the 28th day after drinking vinegar.

Guohua Zeng

Vice President of the Hospital

The First Affiliated Hospital of Guangzhou Medical University

Escitalopram tablet, 10mg, daily, 9 weeks.

Sugar Pill

Active Drug

Total

Sex: Female, Male

Region of Enrollment

Depressive symptoms were assessed by questionaire at baseline and finally at the end of the study at 9 weeks.

Reduction in Depressive Symptoms

Overall Study

Harold Goforth, M.D.

Depression

Placebo daily for duration of double-blind portion of trial

Placebo

Escitalopram 10 mg po daily for duration of double-blind portion of trial

Escitalopram

Duke University Medical Center

A Trial Examining the Efficacy of Escitalopram Oxalate Upon Depressive Symptoms and Fatigue in HIV Seropositive Women

A Double-Blind, Placebo-Controlled Trial Examining the Efficacy of Escitalopram Oxalate Upon Depressive Symptoms and Fatigue in HIV Seropositive Women

Duke University

Participants in this arm were randomized to receive placebo once daily for the first 4 weeks and placebo once daily for the second 4 weeks

Participants in this arm were randomized to receive placebo once daily for the first 4 weeks and escitalopram oxalate 10 mg once daily for the second 4 weeks

Participants in this arm were randomzied to receive escitalopram 10 mg once daily for the first 4 weeks and placebo once daily for the second 4 weeks

Participants in this arm were randomized to receive placebo for the first 4 weeks and placebo for the second 4 weeks

Placebo-Placebo

Participants in this arm were randomized to receive placebo for the first 4 weeks and escitalopram for the second 4 weeks

Placebo-Escitalopram

Participants in this arm were randomzied to receive escitalopram for the first 4 weeks and placebo for the second 4 weeks

Escitalopram-Placebo

Response rate was defined as a 50% reduction in the Hamilton Depression Rating Scale (HAM-D) scores over 4 weeks. The HAM-D can have total scores that range from 0 to 50, with higher scores indicating greater depression. Scores over 14 are considered to be in the depressed range.

Participants in this arm were randomized to receive placebo once daily by mouth for the first 4 weeks and placebo oncedaily by mouth for the second 4 weeks

Participants in this arm were randomized to receive placebo once daily by mouth for the first 4 weeks and escitalopram 10 mg once daily by mouth for the second 4 weeks

Participants in this arm were randomzied to receive escitalopram f10 mg once daily by mouth or the first 4 weeks and placebo once daily by mouth for the second 4 weeks

Depression Response Rate of Escitalopram Oxalate 10 mg Once Daily Compared to Placebo Once Daily for Major Depressive Disorder

Side efect burden was defined as the total score of the UKU Side Effects Rating Scale. This scale contains 48 items corresponding to side effects which are rated from 0-3, with 0 meaning not present and 1-3 rating the severity of the side effect. Higher scores represented greater side effect burden. The scale range is 0 to 144.

Side Effect Burden

The change in HAM-D scores was calculated by subtracting the score at 4 weeks from the score at baseline. The HAM-D can have total scores that range from 0 to 50, with higher scores indicating greater depression. Scores over 14 are considered to be in the depressed range.

Participants in this arm were randomized to receive placebo once daily by mouth for the first 4 weeks and placebo once daily by mouth for the second 4 weeks

Participants in this arm were randomzied to receive escitalopram 10 mg once daily by mouth for the first 4 weeks and placebo once daily by mouth for the second 4 weeks

Change in Hamilton Depression Rating Scale (HAM-D) Scores

Participants in this arm were randomized to receive placebo once daily by mouth for the first 4 weeks and placebo once daily by mouth for the second 4 weeks.

William F Pirl, MD

Colorectal Cancer

Esophageal Cancer

Extrahepatic Bile Duct Cancer

Fatigue

Gallbladder Cancer

Gastric Cancer

Liver Cancer

Lung Cancer

Pancreatic Cancer

escitalopram oxalate 10 mg once daily for 4 weeks

escitalopram oxalate

one placebo pill identical in appearance to the escitalpram pill once daily

oxalate/fatigue

Effect of Vinegar Consumption on 24-hour Urinary Risk Factors Associated With Stone Formation

A Trial Examining the Efficacy of Escitalopram Oxalate Upon Depressive Symptoms and Fatigue in HIV Seropositive Women

Escitalopram in Treating Depression in Patients With Advanced Lung or Gastrointestinal Cancer

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