panaxadiol/panax notoginseng

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[Effects of panaxadiol saponins isolated from Panax notoginseng on intracellular and extracellular calcium].

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Panaxadiol saponins (PDS) contain saponins Panax notoginseng B1 and E. The spontaneous beating induced by isoproterenol in isolated rat right atria and the increase of contractile force induced by Ca2+ in isolated guinea pig colon were inhibited by PDS 75 and 150 micrograms.ml-1, respectively and

An oxepane derivative of panaxadiol from the leaves of Panax notoginseng.

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Hydrolysis of the crude saponin isolated from the leaves of PANAX NOTOGINSENG (Burk.) F. H. Chen yields five sapogenins which are separated by column chromatography. The structures of four of those were elucidated earlier to be panaxadiol, panaxatriol, dammar-20(22)en-3beta, 12beta,26-triol and

[Two new Dammaran sapogenins from leaves of Panax notoginseng.].

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Hydrolysis of the crude saponin extracted from the leaves of Panax notoginseng (Burk.) F. H. Chen yields five sapogenins which are separated by column chromatography. Two of these are identified to be panaxadiol and panaxatriol whose structures were elucidated earlier. The third sapogenin ist found

Dammarane-type leads panaxadiol and protopanaxadiol for drug discovery: Biological activity and structural modification.

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Based on the definite therapeutic benefits, such as neuroprotective, cardioprotective, anticancer, anti-diabetic and so on, the Panax genus which contains many valuable plants, including ginseng (Panax ginseng C.A. Meyer), notoginseng (Panax notoginseng) and American ginseng (Panax quinquefolius

Panaxadiol glycosides that induce neuronal differentiation in neurosphere stem cells.

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Bioassay-guided fractionation, combined with screening based on EGF-responsive neural stem cells (NSCs) differentiation assay, has been used to search for active molecules from Panax notoginseng. Ginsenosides Rg3 (1), Rk1 (2), and Rg5 (3) were identified as potential neurogenic molecules. The

[Screening of plant pathogenic fungi by ginsenoside compound K production].

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OBJECTIVE To screen a new strain which can transform panaxadiol saponins into the rare ginsenoside compound K. METHODS The total saponins in stems and leaves of Panax notoginseng was used as a substrate in the liquid state fermentation process, and the results were detected by TLC and HPLC-ELSD to

20(S)-Protopanaxdiol Suppresses the Abnormal Granule-Monocyte Differentiation of Hematopoietic Stem Cells in 4T1 Breast Cancer-Bearing Mouse.

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Panax notoginseng (PN) has been used as a qi- and blood-activating (Huoxue) drug for thousands of years in China. It has also been widely used as an anticancer drug at present. As a Huoxue drug, the effect of PN on hematopoietic differentiation in tumor-bearing body has

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