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pilocarpine/dichloromethane
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3 hasil
[Determination of three formulations of pilocarpine in rabbit ocular aqueous by RP-HPLC].
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OBJECTIVE
To develop an RP-HPLC method for assay of pilocarpine in rabbit ocular aqueous humor.
METHODS
The RP-HPLC method was performed on a column of ODS-C(18) with the mobile phase consisting of 0.5% of triethylamine (TEA) of phosphate solutions (10 mmol/L, pH 2.5) and acetonitrile (98/2,v/v).
[Ocular pharmacokinetics of 0.5% pilocarpine with sodium hyaluronate in rabbits].
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OBJECTIVE
To compare the pharmacokinetics of 0.5% pilocarpine containing sodium hyaluronate with 1% generic pilocarpine solution.
METHODS
One hundred albino rabbits were divided into 20 groups, each consisting of 5 animals. Ten groups received 0.5% pilocarpine containing sodium hyaluronate and 10
[Ocular pharmacokinetics of pilocarpine micron emulsion in rabbits].
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OBJECTIVE
To compare the pharmacokinetics of pilocarpine micron emulsion with generic pilocarpine solution in the aqueous humor.
METHODS
60 albino rabbits were used and were divided into 20 groups, each consisting of 3 animals. 10 groups received 2% generic pilocarpine 50 microl as controls; 10
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